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Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells

View ORCID ProfileSarah Lensch, Michael H. Herschl, Connor H. Ludwig, Joydeb Sinha, Michaela M. Hinks, View ORCID ProfileAdi Mukund, Taihei Fujimori, Lacramioara Bintu
doi: https://doi.org/10.1101/2021.11.04.467237
Sarah Lensch
1Department of Bioengineering, Stanford University; Stanford, CA 94305, USA
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Michael H. Herschl
1Department of Bioengineering, Stanford University; Stanford, CA 94305, USA
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Connor H. Ludwig
1Department of Bioengineering, Stanford University; Stanford, CA 94305, USA
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Joydeb Sinha
2Department of Chemical and Systems Biology, Stanford University; Stanford, CA 94305, USA
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Michaela M. Hinks
1Department of Bioengineering, Stanford University; Stanford, CA 94305, USA
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Adi Mukund
3Biophysics Program, Stanford University; Stanford, CA 94305, USA
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Taihei Fujimori
1Department of Bioengineering, Stanford University; Stanford, CA 94305, USA
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Lacramioara Bintu
1Department of Bioengineering, Stanford University; Stanford, CA 94305, USA
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  • For correspondence: lbintu@stanford.edu
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Article Information

doi 
https://doi.org/10.1101/2021.11.04.467237
History 
  • November 4, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Sarah Lensch1,
  2. Michael H. Herschl1,
  3. Connor H. Ludwig1,
  4. Joydeb Sinha2,
  5. Michaela M. Hinks1,
  6. Adi Mukund3,
  7. Taihei Fujimori1 and
  8. Lacramioara Bintu1,*
  1. 1Department of Bioengineering, Stanford University; Stanford, CA 94305, USA
  2. 2Department of Chemical and Systems Biology, Stanford University; Stanford, CA 94305, USA
  3. 3Biophysics Program, Stanford University; Stanford, CA 94305, USA
  1. ↵*Corresponding author. Email: lbintu{at}stanford.edu
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Posted November 04, 2021.
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Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells
Sarah Lensch, Michael H. Herschl, Connor H. Ludwig, Joydeb Sinha, Michaela M. Hinks, Adi Mukund, Taihei Fujimori, Lacramioara Bintu
bioRxiv 2021.11.04.467237; doi: https://doi.org/10.1101/2021.11.04.467237
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Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells
Sarah Lensch, Michael H. Herschl, Connor H. Ludwig, Joydeb Sinha, Michaela M. Hinks, Adi Mukund, Taihei Fujimori, Lacramioara Bintu
bioRxiv 2021.11.04.467237; doi: https://doi.org/10.1101/2021.11.04.467237

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