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The Conformational Plasticity of the Selectivity Filter Methionines Controls the In-Cell Cu(I) Uptake through the CTR1 transporter
View ORCID ProfilePavel Janoš, View ORCID ProfileJana Aupič, View ORCID ProfileSharon Ruthstein, View ORCID ProfileAlessandra Magistrato
doi: https://doi.org/10.1101/2021.11.04.467269
Pavel Janoš
aCNR-IOM c/o International School for Advanced studies (SISSA/ISAS), via Bonomea 265, 34136, Trieste, Italy
Jana Aupič
aCNR-IOM c/o International School for Advanced studies (SISSA/ISAS), via Bonomea 265, 34136, Trieste, Italy
Sharon Ruthstein
bDepartment of Chemistry, Faculty of Exact Sciences, and the, Institute for Nanotechnology and Advanced Materials (BINA), Bar-Ilan University, 5290002, Ramat-Gan, Israel
Alessandra Magistrato
aCNR-IOM c/o International School for Advanced studies (SISSA/ISAS), via Bonomea 265, 34136, Trieste, Italy

- Supporting Figures S1-S13[supplements/467269_file02.pdf]
- Movie M1: Cu(I) translocation from Site 1 to Site 2[supplements/467269_file03.mp4]
- Movie M2: Cu(I) dissociation from Site 2[supplements/467269_file04.mp4]
Posted November 04, 2021.
The Conformational Plasticity of the Selectivity Filter Methionines Controls the In-Cell Cu(I) Uptake through the CTR1 transporter
Pavel Janoš, Jana Aupič, Sharon Ruthstein, Alessandra Magistrato
bioRxiv 2021.11.04.467269; doi: https://doi.org/10.1101/2021.11.04.467269
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