A vaccine targeting the L9 epitope of the malaria circumsporozoite protein confers protection from blood-stage infection in a mouse challenge model

Lucie Jelínková; Yevel Flores-Garcia; Sarah Shapiro; Bryce T. Roberts; Nikolai Petrovsky; Fidel Zavala; Bryce Chackerian

doi:10.1101/2021.11.10.465032

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A vaccine targeting the L9 epitope of the malaria circumsporozoite protein confers protection from blood-stage infection in a mouse challenge model

Lucie Jelínková, Yevel Flores-Garcia, Sarah Shapiro, Bryce T. Roberts, View ORCID ProfileNikolai Petrovsky, Fidel Zavala, Bryce Chackerian

doi: https://doi.org/10.1101/2021.11.10.465032

Lucie Jelínková

1Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA

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Yevel Flores-Garcia

2W. Harry Feinstone Department of Molecular Microbiology and Immunology Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

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Sarah Shapiro

2W. Harry Feinstone Department of Molecular Microbiology and Immunology Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

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Bryce T. Roberts

1Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA

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Nikolai Petrovsky

3Vaxine Pty Ltd., 11 Walkley Avenue, Warradale, Adelaide 5046, Australia

4College of Medicine and Public Health, Flinders University, Adelaide 5042, Australia

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ORCID record for Nikolai Petrovsky

Fidel Zavala

2W. Harry Feinstone Department of Molecular Microbiology and Immunology Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA

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Bryce Chackerian

1Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA

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For correspondence: bchackerian@salud.unm.edu

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Posted November 11, 2021.

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A vaccine targeting the L9 epitope of the malaria circumsporozoite protein confers protection from blood-stage infection in a mouse challenge model

Lucie Jelínková, Yevel Flores-Garcia, Sarah Shapiro, Bryce T. Roberts, Nikolai Petrovsky, Fidel Zavala, Bryce Chackerian

bioRxiv 2021.11.10.465032; doi: https://doi.org/10.1101/2021.11.10.465032

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A vaccine targeting the L9 epitope of the malaria circumsporozoite protein confers protection from blood-stage infection in a mouse challenge model

Lucie Jelínková, Yevel Flores-Garcia, Sarah Shapiro, Bryce T. Roberts, Nikolai Petrovsky, Fidel Zavala, Bryce Chackerian

bioRxiv 2021.11.10.465032; doi: https://doi.org/10.1101/2021.11.10.465032

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