Identifying common transcriptome signatures of cancer by interpreting deep learning models

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View ORCID ProfileAnupama Jha, View ORCID ProfileMathieu Quesnel-Vallières, View ORCID ProfileAndrei Thomas-Tikhonenko, Kristen W. Lynch, View ORCID ProfileYoseph Barash

doi: https://doi.org/10.1101/2021.11.11.467790

Anupama Jha

1Department of Computer and Information Science, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA 19104, USA

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ORCID record for Anupama Jha
For correspondence: anupamaj@seas.upenn.edu mathieu.quesnel-vallieres@pennmedicine.upenn.edu yosephb@pennmedicine.upenn.edu

Mathieu Quesnel-Vallières

2Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA

3Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA

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ORCID record for Mathieu Quesnel-Vallières
For correspondence: anupamaj@seas.upenn.edu mathieu.quesnel-vallieres@pennmedicine.upenn.edu yosephb@pennmedicine.upenn.edu

Andrei Thomas-Tikhonenko

4Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA

5Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA

6Division of Cancer Pathobiology, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USA

Kristen W. Lynch

2Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA

3Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA

Yoseph Barash

1Department of Computer and Information Science, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA 19104, USA

3Department of Genetics, University of Pennsylvania, Philadelphia, PA 19104, USA

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ORCID record for Yoseph Barash
For correspondence: anupamaj@seas.upenn.edu mathieu.quesnel-vallieres@pennmedicine.upenn.edu yosephb@pennmedicine.upenn.edu