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Recapitulation of patient-specific 3D chromatin conformation using machine learning and validation of identified enhancer-gene targets

View ORCID ProfileDuo Xu, Andre Neil Forbes, Sandra Cohen, Ann Palladino, Tatiana Karadimitriou, Ekta Khurana
doi: https://doi.org/10.1101/2021.11.16.468857
Duo Xu
1Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA
2Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York, USA
3Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York, USA
4Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA
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  • ORCID record for Duo Xu
Andre Neil Forbes
1Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA
2Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York, USA
5Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, New York, USA
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Sandra Cohen
1Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA
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Ann Palladino
1Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA
2Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York, USA
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Tatiana Karadimitriou
1Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA
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Ekta Khurana
1Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA
2Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York, USA
3Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York, USA
4Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA
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  • For correspondence: ekk2003@med.cornell.edu
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Article Information

doi 
https://doi.org/10.1101/2021.11.16.468857
History 
  • November 19, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Duo Xu1,2,3,4,*,
  2. Andre Neil Forbes1,2,5,*,
  3. Sandra Cohen1,
  4. Ann Palladino1,2,
  5. Tatiana Karadimitriou1 and
  6. Ekta Khurana1,2,3,4,†
  1. 1Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA
  2. 2Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York, USA
  3. 3Department of Physiology and Biophysics, Weill Cornell Medical College, New York, New York, USA
  4. 4Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA
  5. 5Weill Cornell Graduate School of Medical Sciences, Weill Cornell Medicine, New York, New York, USA
  1. ↵†Corresponding authors. Email: ekk2003{at}med.cornell.edu (E.K.)
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Posted November 19, 2021.
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Recapitulation of patient-specific 3D chromatin conformation using machine learning and validation of identified enhancer-gene targets
Duo Xu, Andre Neil Forbes, Sandra Cohen, Ann Palladino, Tatiana Karadimitriou, Ekta Khurana
bioRxiv 2021.11.16.468857; doi: https://doi.org/10.1101/2021.11.16.468857
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Recapitulation of patient-specific 3D chromatin conformation using machine learning and validation of identified enhancer-gene targets
Duo Xu, Andre Neil Forbes, Sandra Cohen, Ann Palladino, Tatiana Karadimitriou, Ekta Khurana
bioRxiv 2021.11.16.468857; doi: https://doi.org/10.1101/2021.11.16.468857

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