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Analysis of the computational strategy of a detailed laminar cortical microcircuit model for solving the image-change-detection task

View ORCID ProfileFranz Scherr, View ORCID ProfileWolfgang Maass
doi: https://doi.org/10.1101/2021.11.17.469025
Franz Scherr
Institute of Theoretical Computer Science, Graz University of Technology, Inffeldgasse 16b, Graz, Austria
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Wolfgang Maass
Institute of Theoretical Computer Science, Graz University of Technology, Inffeldgasse 16b, Graz, Austria
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  • For correspondence: maass@igi.tugraz.at
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Abstract

The neocortex can be viewed as a tapestry consisting of variations of rather stereotypical local cortical microcircuits. Hence understanding how these microcircuits compute holds the key to understanding brain function. Intense research efforts over several decades have culminated in a detailed model of a generic cortical microcircuit in the primary visual cortex from the Allen Institute. We are presenting here methods and first results for understanding computational properties of this largescale data-based model. We show that it can solve a standard image-change-detection task almost as well as the living brain. Furthermore, we unravel the computational strategy of the model and elucidate the computational role of diverse subtypes of neurons. Altogether this work demonstrates the feasibility and scientific potential of a methodology based on close interaction of detailed data and large-scale computer modelling for understanding brain function.

Competing Interest Statement

The authors have declared no competing interest.

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
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Posted November 19, 2021.
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Analysis of the computational strategy of a detailed laminar cortical microcircuit model for solving the image-change-detection task
Franz Scherr, Wolfgang Maass
bioRxiv 2021.11.17.469025; doi: https://doi.org/10.1101/2021.11.17.469025
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Analysis of the computational strategy of a detailed laminar cortical microcircuit model for solving the image-change-detection task
Franz Scherr, Wolfgang Maass
bioRxiv 2021.11.17.469025; doi: https://doi.org/10.1101/2021.11.17.469025

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