New Results
Nonenzymatic loop-closing ligation generates RNA hairpins and is a template-free way to assemble functional RNAs
View ORCID ProfileL.-F. Wu, View ORCID ProfileZ. Liu, View ORCID ProfileS. J. Roberts, View ORCID ProfileM. Su, View ORCID ProfileJ. W. Szostak, J. D. Sutherland
doi: https://doi.org/10.1101/2021.11.19.469337
L.-F. Wu
1MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK
2Howard Hughes Medical Institute, Department of Molecular Biology, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, United States; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, United States
Z. Liu
1MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK
S. J. Roberts
1MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK
M. Su
1MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK
J. W. Szostak
2Howard Hughes Medical Institute, Department of Molecular Biology, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, United States; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, United States
J. D. Sutherland
1MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, CB2 0QH, UK
Article usage
Posted November 19, 2021.
Nonenzymatic loop-closing ligation generates RNA hairpins and is a template-free way to assemble functional RNAs
L.-F. Wu, Z. Liu, S. J. Roberts, M. Su, J. W. Szostak, J. D. Sutherland
bioRxiv 2021.11.19.469337; doi: https://doi.org/10.1101/2021.11.19.469337
Subject Area
Subject Areas
- Biochemistry (11718)
- Bioengineering (8724)
- Bioinformatics (29132)
- Biophysics (14937)
- Cancer Biology (12052)
- Cell Biology (17362)
- Clinical Trials (138)
- Developmental Biology (9407)
- Ecology (14146)
- Epidemiology (2067)
- Evolutionary Biology (18270)
- Genetics (12223)
- Genomics (16768)
- Immunology (11844)
- Microbiology (28016)
- Molecular Biology (11560)
- Neuroscience (60841)
- Paleontology (450)
- Pathology (1864)
- Pharmacology and Toxicology (3231)
- Physiology (4940)
- Plant Biology (10405)
- Synthetic Biology (2878)
- Systems Biology (7333)
- Zoology (1642)