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Single organoid RNA-sequencing reveals high organoid-to-organoid variability

Kristin Gehling, View ORCID ProfileSwati Parekh, Farina Schneider, Marcel Kirchner, View ORCID ProfileVangelis Kondylis, View ORCID ProfileChrysa Nikopoulou, View ORCID ProfilePeter Tessarz
doi: https://doi.org/10.1101/2021.11.22.469588
Kristin Gehling
1Max Planck Research Group “Chromatin and Ageing”, Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Str. 9b, 50931 Cologne, Germany
2Cologne Excellence Cluster on Cellular Stress Responses in Aging-associated Diseases (CECAD), Joseph-Stelzmann-Straße 26, 50931 Cologne, Germany
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Swati Parekh
1Max Planck Research Group “Chromatin and Ageing”, Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Str. 9b, 50931 Cologne, Germany
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  • ORCID record for Swati Parekh
Farina Schneider
3Institute for Pathology, University Hospital Cologne, Kerpener Str. 62, 50937 Cologne, Germany
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Marcel Kirchner
4FACS & Imaging Core Facility, Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Str. 9b, 50931 Cologne, Germany
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Vangelis Kondylis
3Institute for Pathology, University Hospital Cologne, Kerpener Str. 62, 50937 Cologne, Germany
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  • ORCID record for Vangelis Kondylis
Chrysa Nikopoulou
1Max Planck Research Group “Chromatin and Ageing”, Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Str. 9b, 50931 Cologne, Germany
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  • For correspondence: cnikopoulou@age.mpg.de ptessarz@age.mpg.de
Peter Tessarz
1Max Planck Research Group “Chromatin and Ageing”, Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Str. 9b, 50931 Cologne, Germany
2Cologne Excellence Cluster on Cellular Stress Responses in Aging-associated Diseases (CECAD), Joseph-Stelzmann-Straße 26, 50931 Cologne, Germany
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  • ORCID record for Peter Tessarz
  • For correspondence: cnikopoulou@age.mpg.de ptessarz@age.mpg.de
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Article Information

doi 
https://doi.org/10.1101/2021.11.22.469588
History 
  • November 22, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.

Author Information

  1. Kristin Gehling1,2,
  2. Swati Parekh1,
  3. Farina Schneider3,
  4. Marcel Kirchner4,
  5. Vangelis Kondylis3,
  6. Chrysa Nikopoulou1,* and
  7. Peter Tessarz1,2,*
  1. 1Max Planck Research Group “Chromatin and Ageing”, Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Str. 9b, 50931 Cologne, Germany
  2. 2Cologne Excellence Cluster on Cellular Stress Responses in Aging-associated Diseases (CECAD), Joseph-Stelzmann-Straße 26, 50931 Cologne, Germany
  3. 3Institute for Pathology, University Hospital Cologne, Kerpener Str. 62, 50937 Cologne, Germany
  4. 4FACS & Imaging Core Facility, Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Str. 9b, 50931 Cologne, Germany
  1. ↵*correspondence
    : cnikopoulou{at}age.mpg.de, ptessarz{at}age.mpg.de
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Posted November 22, 2021.
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Single organoid RNA-sequencing reveals high organoid-to-organoid variability
Kristin Gehling, Swati Parekh, Farina Schneider, Marcel Kirchner, Vangelis Kondylis, Chrysa Nikopoulou, Peter Tessarz
bioRxiv 2021.11.22.469588; doi: https://doi.org/10.1101/2021.11.22.469588
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Single organoid RNA-sequencing reveals high organoid-to-organoid variability
Kristin Gehling, Swati Parekh, Farina Schneider, Marcel Kirchner, Vangelis Kondylis, Chrysa Nikopoulou, Peter Tessarz
bioRxiv 2021.11.22.469588; doi: https://doi.org/10.1101/2021.11.22.469588

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