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Accurate MHC Motif Deconvolution of Immunopeptidomics Data Reveals a Significant Contribution of DRB3, 4 and 5 to the Total DR Immunopeptidome

View ORCID ProfileSaghar Kaabinejadian, Carolina Barra, View ORCID ProfileBruno Alvarez, View ORCID ProfileHooman Yari, William H Hildebrand, View ORCID ProfileMorten Nielsen
doi: https://doi.org/10.1101/2021.11.23.469647
Saghar Kaabinejadian
1Pure MHC LLC, Oklahoma City, OK 73104, USA
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Carolina Barra
2Department of Health technology, Technical University of Denmark, DK-2800 Lyngby, Denmark
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Bruno Alvarez
3Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín, B 1650 HMP, Buenos Aires, Argentina
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Hooman Yari
4Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
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William H Hildebrand
4Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
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Morten Nielsen
2Department of Health technology, Technical University of Denmark, DK-2800 Lyngby, Denmark
3Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín, B 1650 HMP, Buenos Aires, Argentina
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  • For correspondence: morni@dtu.dk
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Article Information

doi 
https://doi.org/10.1101/2021.11.23.469647
History 
  • November 23, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Saghar Kaabinejadian1,5,
  2. Carolina Barra2,5,
  3. Bruno Alvarez3,
  4. Hooman Yari4,
  5. William H Hildebrand4 and
  6. Morten Nielsen2,3,6,*
  1. 1Pure MHC LLC, Oklahoma City, OK 73104, USA
  2. 2Department of Health technology, Technical University of Denmark, DK-2800 Lyngby, Denmark
  3. 3Instituto de Investigaciones Biotecnológicas, Universidad Nacional de San Martín, B 1650 HMP, Buenos Aires, Argentina
  4. 4Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
  1. ↵*Correspondence: morni{at}dtu.dk
  1. ↵5 These authors contributed equally

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Posted November 23, 2021.
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Accurate MHC Motif Deconvolution of Immunopeptidomics Data Reveals a Significant Contribution of DRB3, 4 and 5 to the Total DR Immunopeptidome
Saghar Kaabinejadian, Carolina Barra, Bruno Alvarez, Hooman Yari, William H Hildebrand, Morten Nielsen
bioRxiv 2021.11.23.469647; doi: https://doi.org/10.1101/2021.11.23.469647
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Accurate MHC Motif Deconvolution of Immunopeptidomics Data Reveals a Significant Contribution of DRB3, 4 and 5 to the Total DR Immunopeptidome
Saghar Kaabinejadian, Carolina Barra, Bruno Alvarez, Hooman Yari, William H Hildebrand, Morten Nielsen
bioRxiv 2021.11.23.469647; doi: https://doi.org/10.1101/2021.11.23.469647

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