Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Host Species is Linked to Pathogen Genotype for the Amphibian Chytrid Fungus (Batrachochytrium dendrobatidis)

View ORCID ProfileAllison Q. Byrne, Anthony W. Waddle, Veronica Saenz, Michel Ohmer, Jef R. Jaeger, Corinne L. Richards-Zawacki, Jamie Voyles, Erica Bree Rosenblum
doi: https://doi.org/10.1101/2021.11.24.469827
Allison Q. Byrne
1Department of Environmental Science, Policy, and Management, University of California Berkeley, Berkeley, CA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Allison Q. Byrne
  • For correspondence: allie128@berkeley.edu
Anthony W. Waddle
2One Health Research Group, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Victoria, Australia
3School of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Veronica Saenz
4Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michel Ohmer
4Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, USA
5Department of Biology, University of Mississippi, University, MS, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jef R. Jaeger
3School of Life Sciences, University of Nevada, Las Vegas, Las Vegas, NV, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Corinne L. Richards-Zawacki
4Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jamie Voyles
6Department of Biology, University of Nevada Reno, Reno, NV, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Erica Bree Rosenblum
1Department of Environmental Science, Policy, and Management, University of California Berkeley, Berkeley, CA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Preview PDF
Loading

Abstract

Host-pathogen specificity can arise from certain selective environments mediated by both the host and pathogen. Therefore, understanding the degree to which host species identity is correlated with pathogen genotype can help reveal historical host-pathogen dynamics. One animal disease of particular concern is chytridiomycosis, typically caused by the global panzootic lineage of the amphibian chytrid fungus (Batrachochytrium dendrobatidis, Bd), termed the Bd-GPL. This pathogen lineage has caused devastating declines in amphibian communities around the world. However, the origin of Bd-GPL and the fine-scale transmission dynamics of this lineage have remained a mystery. This is especially the case in North America where Bd-GPL is widespread, but disease outbreaks occur sporadically. Herein, we use Bd genetic data collected throughout the United States from amphibian skin swab and cultured isolate samples to investigate Bd genetic patterns. We highlight two case studies in Pennsylvania and Nevada where Bd-GPL genotypes are strongly correlated with host species identity. Specifically, in some localities bullfrogs (Rana catesbeiana) are infected with Bd-GPL lineages that are distinct from those infecting other sympatric amphibian species. Overall, we reveal a previously unknown association of Bd genotype with host species and identify the eastern United States as a Bd diversity hotspot and potential ancestral population for Bd-GPL.

Competing Interest Statement

The authors have declared no competing interest.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.
Back to top
PreviousNext
Posted November 24, 2021.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Host Species is Linked to Pathogen Genotype for the Amphibian Chytrid Fungus (Batrachochytrium dendrobatidis)
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Host Species is Linked to Pathogen Genotype for the Amphibian Chytrid Fungus (Batrachochytrium dendrobatidis)
Allison Q. Byrne, Anthony W. Waddle, Veronica Saenz, Michel Ohmer, Jef R. Jaeger, Corinne L. Richards-Zawacki, Jamie Voyles, Erica Bree Rosenblum
bioRxiv 2021.11.24.469827; doi: https://doi.org/10.1101/2021.11.24.469827
Digg logo Reddit logo Twitter logo Facebook logo Google logo LinkedIn logo Mendeley logo
Citation Tools
Host Species is Linked to Pathogen Genotype for the Amphibian Chytrid Fungus (Batrachochytrium dendrobatidis)
Allison Q. Byrne, Anthony W. Waddle, Veronica Saenz, Michel Ohmer, Jef R. Jaeger, Corinne L. Richards-Zawacki, Jamie Voyles, Erica Bree Rosenblum
bioRxiv 2021.11.24.469827; doi: https://doi.org/10.1101/2021.11.24.469827

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Molecular Biology
Subject Areas
All Articles
  • Animal Behavior and Cognition (3688)
  • Biochemistry (7783)
  • Bioengineering (5673)
  • Bioinformatics (21267)
  • Biophysics (10574)
  • Cancer Biology (8170)
  • Cell Biology (11929)
  • Clinical Trials (138)
  • Developmental Biology (6757)
  • Ecology (10394)
  • Epidemiology (2065)
  • Evolutionary Biology (13853)
  • Genetics (9702)
  • Genomics (13063)
  • Immunology (8136)
  • Microbiology (19976)
  • Molecular Biology (7841)
  • Neuroscience (43032)
  • Paleontology (318)
  • Pathology (1278)
  • Pharmacology and Toxicology (2258)
  • Physiology (3350)
  • Plant Biology (7221)
  • Scientific Communication and Education (1311)
  • Synthetic Biology (2000)
  • Systems Biology (5533)
  • Zoology (1127)