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Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer’s disease
Jie Yeap, Chaitra Sathyaprakash, Jamie Toombs, Jane Tulloch, Cristina Scutariu, Jamie Rose, Karen Burr, Caitlin Davies, Marti Colom-Cadena, Siddharthan Chandran, Charles H Large, Matthew JM Rowan, Martin J Gunthorpe, Tara L Spires-Jones
doi: https://doi.org/10.1101/2021.11.24.469829
Jie Yeap
1UK Dementia Research Institute and Centre for Discovery Brain Sciences, University of Edinburgh, UK
Chaitra Sathyaprakash
1UK Dementia Research Institute and Centre for Discovery Brain Sciences, University of Edinburgh, UK
Jamie Toombs
1UK Dementia Research Institute and Centre for Discovery Brain Sciences, University of Edinburgh, UK
Jane Tulloch
1UK Dementia Research Institute and Centre for Discovery Brain Sciences, University of Edinburgh, UK
Cristina Scutariu
1UK Dementia Research Institute and Centre for Discovery Brain Sciences, University of Edinburgh, UK
Jamie Rose
1UK Dementia Research Institute and Centre for Discovery Brain Sciences, University of Edinburgh, UK
Karen Burr
2UK Dementia Research Institute and Centre for Clinical Brain Sciences, University of Edinburgh UK
Caitlin Davies
1UK Dementia Research Institute and Centre for Discovery Brain Sciences, University of Edinburgh, UK
Marti Colom-Cadena
1UK Dementia Research Institute and Centre for Discovery Brain Sciences, University of Edinburgh, UK
Siddharthan Chandran
2UK Dementia Research Institute and Centre for Clinical Brain Sciences, University of Edinburgh UK
Charles H Large
3Autifony Therapeutics Limited, Stevenage Bioscience Catalyst, Stevenage, UK
Matthew JM Rowan
4Emory University School of Medicine, Atlanta, GA, USA
Martin J Gunthorpe
3Autifony Therapeutics Limited, Stevenage Bioscience Catalyst, Stevenage, UK
Tara L Spires-Jones
1UK Dementia Research Institute and Centre for Discovery Brain Sciences, University of Edinburgh, UK
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Posted November 25, 2021.
Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer’s disease
Jie Yeap, Chaitra Sathyaprakash, Jamie Toombs, Jane Tulloch, Cristina Scutariu, Jamie Rose, Karen Burr, Caitlin Davies, Marti Colom-Cadena, Siddharthan Chandran, Charles H Large, Matthew JM Rowan, Martin J Gunthorpe, Tara L Spires-Jones
bioRxiv 2021.11.24.469829; doi: https://doi.org/10.1101/2021.11.24.469829
Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimer’s disease
Jie Yeap, Chaitra Sathyaprakash, Jamie Toombs, Jane Tulloch, Cristina Scutariu, Jamie Rose, Karen Burr, Caitlin Davies, Marti Colom-Cadena, Siddharthan Chandran, Charles H Large, Matthew JM Rowan, Martin J Gunthorpe, Tara L Spires-Jones
bioRxiv 2021.11.24.469829; doi: https://doi.org/10.1101/2021.11.24.469829
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