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A spatial multi-omics atlas of the human lung reveals a novel immune cell survival niche
View ORCID ProfileElo Madissoon, View ORCID ProfileAmanda J. Oliver, View ORCID ProfileVitalii Kleshchevnikov, Anna Wilbrey-Clark, View ORCID ProfileKrzysztof Polanski, View ORCID ProfileAna Ribeiro Orsi, Lira Mamanova, View ORCID ProfileLiam Bolt, Nathan Richoz, View ORCID ProfileRasa Elmentaite, View ORCID ProfileJ. Patrick Pett, Ni Huang, View ORCID ProfilePeng He, Monika Dabrowska, View ORCID ProfileSophie Pritchard, Liz Tuck, View ORCID ProfileElena Prigmore, View ORCID ProfileAndrew Knights, View ORCID ProfileAgnes Oszlanczi, View ORCID ProfileAdam Hunter, View ORCID ProfileSara F. Vieira, Minal Patel, View ORCID ProfileNikitas Georgakopoulos, View ORCID ProfileKrishnaa Mahbubani, View ORCID ProfileKourosh Saeb-Parsy, View ORCID ProfileMenna Clatworthy, View ORCID ProfileOmer Ali Bayraktar, View ORCID ProfileOliver Stegle, View ORCID ProfileNatsuhiko Kumasaka, View ORCID ProfileSarah A. Teichmann, View ORCID ProfileKerstin B. Meyer
doi: https://doi.org/10.1101/2021.11.26.470108
Elo Madissoon
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
2European Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Wellcome Trust Genome Campus, Hinxton CB10 1SD, UK
Amanda J. Oliver
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Vitalii Kleshchevnikov
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Anna Wilbrey-Clark
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Krzysztof Polanski
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Ana Ribeiro Orsi
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
3Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, SP 05508-090, São Paulo, Brazil
Lira Mamanova
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Liam Bolt
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Nathan Richoz
4Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Ave, Cambridge CB2 OQH, UK
Rasa Elmentaite
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
J. Patrick Pett
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Ni Huang
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Peng He
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Monika Dabrowska
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Sophie Pritchard
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Liz Tuck
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Elena Prigmore
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Andrew Knights
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Agnes Oszlanczi
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Adam Hunter
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Sara F. Vieira
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Minal Patel
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Nikitas Georgakopoulos
5Department of Surgery, University of Cambridge, and Cambridge NIHR Biomedical Research Centre, Cambridge, CB2 0QQ, UK
Krishnaa Mahbubani
5Department of Surgery, University of Cambridge, and Cambridge NIHR Biomedical Research Centre, Cambridge, CB2 0QQ, UK
Kourosh Saeb-Parsy
5Department of Surgery, University of Cambridge, and Cambridge NIHR Biomedical Research Centre, Cambridge, CB2 0QQ, UK
Menna Clatworthy
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
4Department of Medicine, University of Cambridge, MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Ave, Cambridge CB2 OQH, UK
Omer Ali Bayraktar
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Oliver Stegle
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
6European Molecular Biology Laboratory EMBL, Heidelberg, Meyerhofstraße 1, 69117 Heidelberg, Germany
7Deutsches Krebsforschungszentrum DKFZ, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
Natsuhiko Kumasaka
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Sarah A. Teichmann
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
8Theory of Condensed Matter, Cavendish Laboratory/Dept Physics, University of Cambridge, JJ Thomson Ave, Cambridge CB3 0HE, UK
Kerstin B. Meyer
1Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK
Article usage
Posted November 27, 2021.
A spatial multi-omics atlas of the human lung reveals a novel immune cell survival niche
Elo Madissoon, Amanda J. Oliver, Vitalii Kleshchevnikov, Anna Wilbrey-Clark, Krzysztof Polanski, Ana Ribeiro Orsi, Lira Mamanova, Liam Bolt, Nathan Richoz, Rasa Elmentaite, J. Patrick Pett, Ni Huang, Peng He, Monika Dabrowska, Sophie Pritchard, Liz Tuck, Elena Prigmore, Andrew Knights, Agnes Oszlanczi, Adam Hunter, Sara F. Vieira, Minal Patel, Nikitas Georgakopoulos, Krishnaa Mahbubani, Kourosh Saeb-Parsy, Menna Clatworthy, Omer Ali Bayraktar, Oliver Stegle, Natsuhiko Kumasaka, Sarah A. Teichmann, Kerstin B. Meyer
bioRxiv 2021.11.26.470108; doi: https://doi.org/10.1101/2021.11.26.470108
A spatial multi-omics atlas of the human lung reveals a novel immune cell survival niche
Elo Madissoon, Amanda J. Oliver, Vitalii Kleshchevnikov, Anna Wilbrey-Clark, Krzysztof Polanski, Ana Ribeiro Orsi, Lira Mamanova, Liam Bolt, Nathan Richoz, Rasa Elmentaite, J. Patrick Pett, Ni Huang, Peng He, Monika Dabrowska, Sophie Pritchard, Liz Tuck, Elena Prigmore, Andrew Knights, Agnes Oszlanczi, Adam Hunter, Sara F. Vieira, Minal Patel, Nikitas Georgakopoulos, Krishnaa Mahbubani, Kourosh Saeb-Parsy, Menna Clatworthy, Omer Ali Bayraktar, Oliver Stegle, Natsuhiko Kumasaka, Sarah A. Teichmann, Kerstin B. Meyer
bioRxiv 2021.11.26.470108; doi: https://doi.org/10.1101/2021.11.26.470108
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