New Results
Case Study of High-Throughput Drug Screening and Remote Data Collection for SARS-CoV-2 Main Protease by Using Serial Femtosecond X-ray Crystallography
View ORCID ProfileOmur Guven, View ORCID ProfileMehmet Gul, Esra Ayan, J. Austin Johnson, Baris Cakilkaya, Gozde Usta, View ORCID ProfileFatma Betul Ertem, View ORCID ProfileNurettin Tokay, View ORCID ProfileBusra Yuksel, View ORCID ProfileOktay Gocenler, View ORCID ProfileCengizhan Buyukdag, View ORCID ProfileSabine Botha, View ORCID ProfileGihan Ketawala, Zhen Su, Brandon Hayes, View ORCID ProfileFrederic Poitevin, Alexander Batyuk, Chun Hong Yoon, Christopher Kupitz, View ORCID ProfileSerdar Durdagi, View ORCID ProfileRaymond G. Sierra, View ORCID ProfileHasan DeMirci
doi: https://doi.org/10.1101/2021.11.28.468932
Omur Guven
1Department of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey
Mehmet Gul
1Department of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey
Esra Ayan
1Department of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey
J. Austin Johnson
1Department of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey
Baris Cakilkaya
1Department of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey
Gozde Usta
1Department of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey
Fatma Betul Ertem
1Department of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey
Nurettin Tokay
1Department of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey
Busra Yuksel
1Department of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey
Oktay Gocenler
1Department of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey
Cengizhan Buyukdag
1Department of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey
Sabine Botha
2Department of Physics, Arizona State University, Tempe, AZ 85287-1504, USA
3Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ 85287-5001, USA
Gihan Ketawala
2Department of Physics, Arizona State University, Tempe, AZ 85287-1504, USA
3Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ 85287-5001, USA
Zhen Su
4Linac Coherent Light Source, SLAC National Accelerator Laboratory, 2575 Sand Hill Rd, Menlo Park, 94025, CA, USA
Brandon Hayes
4Linac Coherent Light Source, SLAC National Accelerator Laboratory, 2575 Sand Hill Rd, Menlo Park, 94025, CA, USA
Frederic Poitevin
4Linac Coherent Light Source, SLAC National Accelerator Laboratory, 2575 Sand Hill Rd, Menlo Park, 94025, CA, USA
Alexander Batyuk
4Linac Coherent Light Source, SLAC National Accelerator Laboratory, 2575 Sand Hill Rd, Menlo Park, 94025, CA, USA
Chun Hong Yoon
4Linac Coherent Light Source, SLAC National Accelerator Laboratory, 2575 Sand Hill Rd, Menlo Park, 94025, CA, USA
Christopher Kupitz
4Linac Coherent Light Source, SLAC National Accelerator Laboratory, 2575 Sand Hill Rd, Menlo Park, 94025, CA, USA
Serdar Durdagi
5Computational Biology and Molecular Simulations Laboratory, Department of Biophysics, School of Medicine, Bahcesehir University, Istanbul 34734, Turkey
Raymond G. Sierra
4Linac Coherent Light Source, SLAC National Accelerator Laboratory, 2575 Sand Hill Rd, Menlo Park, 94025, CA, USA
Hasan DeMirci
1Department of Molecular Biology and Genetics, Koc University, 34450, Istanbul, Turkey
6Koc University Isbank Center for Infectious Diseases (KUISCID), 34010, Istanbul, Turkey
7Stanford PULSE Institute, SLAC National Laboratory, Menlo Park, CA 94025, USA
Article usage
Posted November 30, 2021.
Case Study of High-Throughput Drug Screening and Remote Data Collection for SARS-CoV-2 Main Protease by Using Serial Femtosecond X-ray Crystallography
Omur Guven, Mehmet Gul, Esra Ayan, J. Austin Johnson, Baris Cakilkaya, Gozde Usta, Fatma Betul Ertem, Nurettin Tokay, Busra Yuksel, Oktay Gocenler, Cengizhan Buyukdag, Sabine Botha, Gihan Ketawala, Zhen Su, Brandon Hayes, Frederic Poitevin, Alexander Batyuk, Chun Hong Yoon, Christopher Kupitz, Serdar Durdagi, Raymond G. Sierra, Hasan DeMirci
bioRxiv 2021.11.28.468932; doi: https://doi.org/10.1101/2021.11.28.468932
Case Study of High-Throughput Drug Screening and Remote Data Collection for SARS-CoV-2 Main Protease by Using Serial Femtosecond X-ray Crystallography
Omur Guven, Mehmet Gul, Esra Ayan, J. Austin Johnson, Baris Cakilkaya, Gozde Usta, Fatma Betul Ertem, Nurettin Tokay, Busra Yuksel, Oktay Gocenler, Cengizhan Buyukdag, Sabine Botha, Gihan Ketawala, Zhen Su, Brandon Hayes, Frederic Poitevin, Alexander Batyuk, Chun Hong Yoon, Christopher Kupitz, Serdar Durdagi, Raymond G. Sierra, Hasan DeMirci
bioRxiv 2021.11.28.468932; doi: https://doi.org/10.1101/2021.11.28.468932
Subject Area
Subject Areas
- Biochemistry (11744)
- Bioengineering (8751)
- Bioinformatics (29193)
- Biophysics (14968)
- Cancer Biology (12094)
- Cell Biology (17411)
- Clinical Trials (138)
- Developmental Biology (9421)
- Ecology (14178)
- Epidemiology (2067)
- Evolutionary Biology (18303)
- Genetics (12244)
- Genomics (16801)
- Immunology (11866)
- Microbiology (28082)
- Molecular Biology (11592)
- Neuroscience (60959)
- Paleontology (451)
- Pathology (1870)
- Pharmacology and Toxicology (3238)
- Physiology (4957)
- Plant Biology (10427)
- Synthetic Biology (2885)
- Systems Biology (7339)
- Zoology (1651)