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Intrathecal sc-AAV9-CB-GFP: Systemic Distribution Predominates Following Single-Dose Administration in Cynomolgus Macaques

View ORCID ProfileEmily K. Meseck, Ghiabe Guibinga, Stephen Wang, Cameron McElroy, Eloise Hudry, Keith Mansfield
doi: https://doi.org/10.1101/2021.11.28.470258
Emily K. Meseck
1Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA
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  • For correspondence: emily.meseck@novartis.com
Ghiabe Guibinga
2Novartis Institutes for BioMedical Research Biologics Center, San Diego, CA, USA
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Stephen Wang
3Novartis Institutes for BioMedical Research, Cambridge, MA, USA
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Cameron McElroy
1Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA
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Eloise Hudry
3Novartis Institutes for BioMedical Research, Cambridge, MA, USA
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Keith Mansfield
3Novartis Institutes for BioMedical Research, Cambridge, MA, USA
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Article Information

doi 
https://doi.org/10.1101/2021.11.28.470258
History 
  • November 28, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Emily K. Meseck1,*,
  2. Ghiabe Guibinga2,
  3. Stephen Wang3,
  4. Cameron McElroy1,
  5. Eloise Hudry3 and
  6. Keith Mansfield3
  1. 1Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA
  2. 2Novartis Institutes for BioMedical Research Biologics Center, San Diego, CA, USA
  3. 3Novartis Institutes for BioMedical Research, Cambridge, MA, USA
  1. ↵*Corresponding Author: Emily K. Meseck, Novartis Pharmaceuticals 436/4223 One Health Plaza East Hanover, NJ 07936 Telephone: 1-862-778-7667, E-mail: emily.meseck{at}novartis.com
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Posted November 28, 2021.
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Intrathecal sc-AAV9-CB-GFP: Systemic Distribution Predominates Following Single-Dose Administration in Cynomolgus Macaques
Emily K. Meseck, Ghiabe Guibinga, Stephen Wang, Cameron McElroy, Eloise Hudry, Keith Mansfield
bioRxiv 2021.11.28.470258; doi: https://doi.org/10.1101/2021.11.28.470258
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Intrathecal sc-AAV9-CB-GFP: Systemic Distribution Predominates Following Single-Dose Administration in Cynomolgus Macaques
Emily K. Meseck, Ghiabe Guibinga, Stephen Wang, Cameron McElroy, Eloise Hudry, Keith Mansfield
bioRxiv 2021.11.28.470258; doi: https://doi.org/10.1101/2021.11.28.470258

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