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Intrathecal sc-AAV9-CB-GFP: Systemic Distribution Predominates Following Single-Dose Administration in Cynomolgus Macaques

View ORCID ProfileEmily K. Meseck, Ghiabe Guibinga, Stephen Wang, Cameron McElroy, Eloise Hudry, Keith Mansfield
doi: https://doi.org/10.1101/2021.11.28.470258
Emily K. Meseck
1Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA
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  • For correspondence: emily.meseck@novartis.com
Ghiabe Guibinga
2Novartis Institutes for BioMedical Research Biologics Center, San Diego, CA, USA
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Stephen Wang
3Novartis Institutes for BioMedical Research, Cambridge, MA, USA
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Cameron McElroy
1Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA
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Eloise Hudry
3Novartis Institutes for BioMedical Research, Cambridge, MA, USA
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Keith Mansfield
3Novartis Institutes for BioMedical Research, Cambridge, MA, USA
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  • Supplemental tables and data for Biodistribution, molecular pathology and pathology[supplements/470258_file02.docx]
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Posted November 28, 2021.
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Intrathecal sc-AAV9-CB-GFP: Systemic Distribution Predominates Following Single-Dose Administration in Cynomolgus Macaques
Emily K. Meseck, Ghiabe Guibinga, Stephen Wang, Cameron McElroy, Eloise Hudry, Keith Mansfield
bioRxiv 2021.11.28.470258; doi: https://doi.org/10.1101/2021.11.28.470258
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Intrathecal sc-AAV9-CB-GFP: Systemic Distribution Predominates Following Single-Dose Administration in Cynomolgus Macaques
Emily K. Meseck, Ghiabe Guibinga, Stephen Wang, Cameron McElroy, Eloise Hudry, Keith Mansfield
bioRxiv 2021.11.28.470258; doi: https://doi.org/10.1101/2021.11.28.470258

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