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RNA-guided cell targeting with CRISPR/RfxCas13d collateral activity in human cells

Peiguo Shi, Michael R. Murphy, Alexis O. Aparicio, Jordan S. Kesner, Zhou Fang, Ziheng Chen, Aditi Trehan, View ORCID ProfileXuebing Wu
doi: https://doi.org/10.1101/2021.11.30.470032
Peiguo Shi
1Department of Medicine and Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA
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  • For correspondence: ps3008@cumc.columbia.edu xw2629@cumc.columbia.edu
Michael R. Murphy
1Department of Medicine and Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA
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Alexis O. Aparicio
1Department of Medicine and Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA
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Jordan S. Kesner
1Department of Medicine and Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA
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Zhou Fang
1Department of Medicine and Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA
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Ziheng Chen
1Department of Medicine and Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA
2Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213, USA
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Aditi Trehan
1Department of Medicine and Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA
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Xuebing Wu
1Department of Medicine and Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA
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  • ORCID record for Xuebing Wu
  • For correspondence: ps3008@cumc.columbia.edu xw2629@cumc.columbia.edu
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Article Information

doi 
https://doi.org/10.1101/2021.11.30.470032
History 
  • November 30, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Peiguo Shi1,*,
  2. Michael R. Murphy1,
  3. Alexis O. Aparicio1,
  4. Jordan S. Kesner1,
  5. Zhou Fang1,
  6. Ziheng Chen1,2,
  7. Aditi Trehan1 and
  8. Xuebing Wu1,*
  1. 1Department of Medicine and Department of Systems Biology, Columbia University Irving Medical Center, New York, NY 10032, USA
  2. 2Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213, USA
  1. ↵*Correspondence to: ps3008{at}cumc.columbia.edu (P.S.), xw2629{at}cumc.columbia.edu (X.W.)
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Posted November 30, 2021.
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RNA-guided cell targeting with CRISPR/RfxCas13d collateral activity in human cells
Peiguo Shi, Michael R. Murphy, Alexis O. Aparicio, Jordan S. Kesner, Zhou Fang, Ziheng Chen, Aditi Trehan, Xuebing Wu
bioRxiv 2021.11.30.470032; doi: https://doi.org/10.1101/2021.11.30.470032
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RNA-guided cell targeting with CRISPR/RfxCas13d collateral activity in human cells
Peiguo Shi, Michael R. Murphy, Alexis O. Aparicio, Jordan S. Kesner, Zhou Fang, Ziheng Chen, Aditi Trehan, Xuebing Wu
bioRxiv 2021.11.30.470032; doi: https://doi.org/10.1101/2021.11.30.470032

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