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Early life energy expenditure deficits drive obesity in a mouse model of Alström syndrome

View ORCID ProfileErin J Stephenson, Clint E Kinney, Amanda S Statyton, View ORCID ProfileJoan C Han
doi: https://doi.org/10.1101/2021.12.03.471145
Erin J Stephenson
1Department of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, 38164, U.S.A.
3Children’s Foundation Research Institute, Le Bonheur Children’s Hospital, Memphis, TN, 38104, U.S.A.
4Department of Anatomy, College of Graduate Studies and Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, IL 60515, U.S.A.
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Clint E Kinney
1Department of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, 38164, U.S.A.
3Children’s Foundation Research Institute, Le Bonheur Children’s Hospital, Memphis, TN, 38104, U.S.A.
5Department of Pediatrics, Icahn School of Medicine at Mount Sinai and Kravis Children’s Hospital, New York, NY, U.S.A.
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Amanda S Statyton
1Department of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, 38164, U.S.A.
3Children’s Foundation Research Institute, Le Bonheur Children’s Hospital, Memphis, TN, 38104, U.S.A.
6James D. Eason Transplant Institute, Department of Surgery, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, 38164, U.S.A.
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Joan C Han
1Department of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, 38164, U.S.A.
2Department of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, 38164, U.S.A.
3Children’s Foundation Research Institute, Le Bonheur Children’s Hospital, Memphis, TN, 38104, U.S.A.
5Department of Pediatrics, Icahn School of Medicine at Mount Sinai and Kravis Children’s Hospital, New York, NY, U.S.A.
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  • ORCID record for Joan C Han
  • For correspondence: esteph@midwestern.edu
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Article Information

doi 
https://doi.org/10.1101/2021.12.03.471145
History 
  • December 4, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Erin J Stephenson1,3,4,
  2. Clint E Kinney1,3,5,
  3. Amanda S Statyton1,3,6 and
  4. Joan C Han1,2,3,5,*
  1. 1Department of Pediatrics, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, 38164, U.S.A.
  2. 2Department of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, 38164, U.S.A.
  3. 3Children’s Foundation Research Institute, Le Bonheur Children’s Hospital, Memphis, TN, 38104, U.S.A.
  4. 4Department of Anatomy, College of Graduate Studies and Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, IL 60515, U.S.A.
  5. 5Department of Pediatrics, Icahn School of Medicine at Mount Sinai and Kravis Children’s Hospital, New York, NY, U.S.A.
  6. 6James D. Eason Transplant Institute, Department of Surgery, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, 38164, U.S.A.
  1. ↵*Corresponding author, esteph{at}midwestern.edu
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Posted December 04, 2021.
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Early life energy expenditure deficits drive obesity in a mouse model of Alström syndrome
Erin J Stephenson, Clint E Kinney, Amanda S Statyton, Joan C Han
bioRxiv 2021.12.03.471145; doi: https://doi.org/10.1101/2021.12.03.471145
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Early life energy expenditure deficits drive obesity in a mouse model of Alström syndrome
Erin J Stephenson, Clint E Kinney, Amanda S Statyton, Joan C Han
bioRxiv 2021.12.03.471145; doi: https://doi.org/10.1101/2021.12.03.471145

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