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Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells
View ORCID ProfileMatias I. Autio, Efthymios Motakis, Arnaud Perrin, Talal Bin Amin, Zenia Tiang, Dang Vinh Do, Jiaxu Wang, Joanna Tan, Wei Xuan Tan, Adrian Kee Keong Teo, View ORCID ProfileRoger S.-Y. Foo
doi: https://doi.org/10.1101/2021.12.07.471422
Matias I. Autio
1Laboratory of Molecular Epigenomics and Chromatin Organization, Genome Institute of Singapore, A*STAR, 138672, Singapore
2Cardiovascular Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, 117599, Singapore
Efthymios Motakis
2Cardiovascular Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, 117599, Singapore
Arnaud Perrin
1Laboratory of Molecular Epigenomics and Chromatin Organization, Genome Institute of Singapore, A*STAR, 138672, Singapore
2Cardiovascular Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, 117599, Singapore
Talal Bin Amin
3Laboratory of Systems Biology and Data Analytics, Genome Institute of Singapore, A*STAR, 138672, Singapore
Zenia Tiang
1Laboratory of Molecular Epigenomics and Chromatin Organization, Genome Institute of Singapore, A*STAR, 138672, Singapore
2Cardiovascular Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, 117599, Singapore
Dang Vinh Do
1Laboratory of Molecular Epigenomics and Chromatin Organization, Genome Institute of Singapore, A*STAR, 138672, Singapore
2Cardiovascular Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, 117599, Singapore
Jiaxu Wang
4Laboratory of RNA Genomics and Structure, Genome Institute of Singapore, A*STAR, 138672, Singapore
Joanna Tan
5Center for Genome Diagnostics, Genome Institute of Singapore, A*STAR, 138672, Singapore
Wei Xuan Tan
6Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology, A*STAR, 138673, Singapore
7Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 119228, Singapore
Adrian Kee Keong Teo
6Stem Cells and Diabetes Laboratory, Institute of Molecular and Cell Biology, A*STAR, 138673, Singapore
7Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 119228, Singapore
8Precision Medicine Translational Research Programme, Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 117596, Singapore
Roger S.-Y. Foo
1Laboratory of Molecular Epigenomics and Chromatin Organization, Genome Institute of Singapore, A*STAR, 138672, Singapore
2Cardiovascular Disease Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, 117599, Singapore
Posted January 25, 2022.
Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells
Matias I. Autio, Efthymios Motakis, Arnaud Perrin, Talal Bin Amin, Zenia Tiang, Dang Vinh Do, Jiaxu Wang, Joanna Tan, Wei Xuan Tan, Adrian Kee Keong Teo, Roger S.-Y. Foo
bioRxiv 2021.12.07.471422; doi: https://doi.org/10.1101/2021.12.07.471422
Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells
Matias I. Autio, Efthymios Motakis, Arnaud Perrin, Talal Bin Amin, Zenia Tiang, Dang Vinh Do, Jiaxu Wang, Joanna Tan, Wei Xuan Tan, Adrian Kee Keong Teo, Roger S.-Y. Foo
bioRxiv 2021.12.07.471422; doi: https://doi.org/10.1101/2021.12.07.471422
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