Structural models of SARS-CoV-2 Omicron variant in complex with ACE2 receptor or antibodies suggest altered binding interfaces

Joseph H. Lubin; Christopher Markosian; D. Balamurugan; Renata Pasqualini; Wadih Arap; Stephen K. Burley; Sagar D. Khare

doi:10.1101/2021.12.12.472313

New Results

Structural models of SARS-CoV-2 Omicron variant in complex with ACE2 receptor or antibodies suggest altered binding interfaces

Joseph H. Lubin, Christopher Markosian, D. Balamurugan, Renata Pasqualini, Wadih Arap, Stephen K. Burley, Sagar D. Khare

doi: https://doi.org/10.1101/2021.12.12.472313

Joseph H. Lubin

1Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Christopher Markosian

2Rutgers Cancer Institute of New Jersey, Newark, NJ 07101

3Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

D. Balamurugan

4Office of Advanced Research Computing, Rutgers, The State University of New Jersey, Piscataway, NJ 08854

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Renata Pasqualini

2Rutgers Cancer Institute of New Jersey, Newark, NJ 07101

3Division of Cancer Biology, Department of Radiation Oncology, Rutgers New Jersey Medical School, Newark, NJ 07103

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Wadih Arap

2Rutgers Cancer Institute of New Jersey, Newark, NJ 07101

5Division of Hematology/Oncology, Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ 07103

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Stephen K. Burley

1Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854

6RCSB Protein Data Bank, Rutgers, The State University of New Jersey, Piscataway, NJ 08854

7RCSB Protein Data Bank, San Diego Supercomputer Center and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92067

8Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901

9Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, NJ 08854

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Sagar D. Khare

1Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854

8Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901

9Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, NJ 08854

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: khare@chem.rutgers.edu

Abstract
Full Text
Info/History
Metrics
Supplementary material
Data/Code
Preview PDF

Supplementary Materials[supplements/472313_file13.pdf]

View the discussion thread.

PreviousNext

Posted December 13, 2021.

Download PDF

Supplementary Material

Data/Code

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Structural models of SARS-CoV-2 Omicron variant in complex with ACE2 receptor or antibodies suggest altered binding interfaces

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Structural models of SARS-CoV-2 Omicron variant in complex with ACE2 receptor or antibodies suggest altered binding interfaces

Joseph H. Lubin, Christopher Markosian, D. Balamurugan, Renata Pasqualini, Wadih Arap, Stephen K. Burley, Sagar D. Khare

bioRxiv 2021.12.12.472313; doi: https://doi.org/10.1101/2021.12.12.472313

Share This Article:

Citation Tools

Structural models of SARS-CoV-2 Omicron variant in complex with ACE2 receptor or antibodies suggest altered binding interfaces

Joseph H. Lubin, Christopher Markosian, D. Balamurugan, Renata Pasqualini, Wadih Arap, Stephen K. Burley, Sagar D. Khare

bioRxiv 2021.12.12.472313; doi: https://doi.org/10.1101/2021.12.12.472313

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Tweet Widget
Facebook Like
Google Plus One

Subject Area

Biophysics

Subject Areas

All Articles

Animal Behavior and Cognition (4370)
Biochemistry (9559)
Bioengineering (7075)
Bioinformatics (24788)
Biophysics (12576)
Cancer Biology (9927)
Cell Biology (14304)
Clinical Trials (138)
Developmental Biology (7934)
Ecology (12084)
Epidemiology (2067)
Evolutionary Biology (15963)
Genetics (10906)
Genomics (14714)
Immunology (9848)
Microbiology (23595)
Molecular Biology (9461)
Neuroscience (50727)
Paleontology (369)
Pathology (1537)
Pharmacology and Toxicology (2675)
Physiology (4001)
Plant Biology (8646)
Scientific Communication and Education (1505)
Synthetic Biology (2388)
Systems Biology (6417)
Zoology (1345)