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Multiple phage resistance systems inhibit infection via SIR2-dependent NAD+ depletion

Jeremy Garb, Anna Lopatina, Aude Bernheim, Mindaugas Zaremba, Virginijus Siksnys, Sarah Melamed, Azita Leavitt, Adi Millman, Gil Amitai, Rotem Sorek
doi: https://doi.org/10.1101/2021.12.14.472415

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doi 
https://doi.org/10.1101/2021.12.14.472415
History 
  • December 14, 2021.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Jeremy Garb1,
  2. Anna Lopatina1,‡,
  3. Aude Bernheim1,#,
  4. Mindaugas Zaremba2,
  5. Virginijus Siksnys2,
  6. Sarah Melamed1,
  7. Azita Leavitt1,
  8. Adi Millman1,
  9. Gil Amitai1 and
  10. Rotem Sorek1,*
  1. 1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel
  2. 2Institute of Biotechnology, Life Sciences Center, Vilnius University, Sauletekio al. 7, LT-10257 Vilnius, Lithuania
  1. ↵*correspondence: rotem.sorek{at}weizmann.ac.il

  • ↵‡ Division of Microbial Ecology, Department of Microbiology and Ecosystem Science, Center for Microbiology and Environmental Systems Science, University of Vienna, Vienna, Austria.

  • ↵# Université de Paris, IAME, UMR 1137, INSERM, Paris, France.

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Posted December 14, 2021.
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Multiple phage resistance systems inhibit infection via SIR2-dependent NAD+ depletion
Jeremy Garb, Anna Lopatina, Aude Bernheim, Mindaugas Zaremba, Virginijus Siksnys, Sarah Melamed, Azita Leavitt, Adi Millman, Gil Amitai, Rotem Sorek
bioRxiv 2021.12.14.472415; doi: https://doi.org/10.1101/2021.12.14.472415
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