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Multiple phage resistance systems inhibit infection via SIR2-dependent NAD+ depletion

Jeremy Garb, Anna Lopatina, Aude Bernheim, Mindaugas Zaremba, Virginijus Siksnys, Sarah Melamed, Azita Leavitt, Adi Millman, Gil Amitai, Rotem Sorek
doi: https://doi.org/10.1101/2021.12.14.472415
Jeremy Garb
1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel
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Anna Lopatina
1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel
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Aude Bernheim
1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel
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Mindaugas Zaremba
2Institute of Biotechnology, Life Sciences Center, Vilnius University, Sauletekio al. 7, LT-10257 Vilnius, Lithuania
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Virginijus Siksnys
2Institute of Biotechnology, Life Sciences Center, Vilnius University, Sauletekio al. 7, LT-10257 Vilnius, Lithuania
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Sarah Melamed
1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel
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Azita Leavitt
1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel
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Adi Millman
1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel
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Gil Amitai
1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel
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Rotem Sorek
1Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel
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  • For correspondence: rotem.sorek@weizmann.ac.il
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Posted December 14, 2021.
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Multiple phage resistance systems inhibit infection via SIR2-dependent NAD+ depletion
Jeremy Garb, Anna Lopatina, Aude Bernheim, Mindaugas Zaremba, Virginijus Siksnys, Sarah Melamed, Azita Leavitt, Adi Millman, Gil Amitai, Rotem Sorek
bioRxiv 2021.12.14.472415; doi: https://doi.org/10.1101/2021.12.14.472415
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Multiple phage resistance systems inhibit infection via SIR2-dependent NAD+ depletion
Jeremy Garb, Anna Lopatina, Aude Bernheim, Mindaugas Zaremba, Virginijus Siksnys, Sarah Melamed, Azita Leavitt, Adi Millman, Gil Amitai, Rotem Sorek
bioRxiv 2021.12.14.472415; doi: https://doi.org/10.1101/2021.12.14.472415

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