New Results
Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications
View ORCID ProfileLorna Ewart, View ORCID ProfileAthanasia Apostolou, Skyler A. Briggs, View ORCID ProfileChristopher V. Carman, Jake T. Chaff, Anthony R. Heng, Sushma Jadalannagari, View ORCID ProfileJeshina Janardhanan, Kyung-Jin Jang, Sannidhi R. Joshipura, Mahika M. Kadam, View ORCID ProfileMarianne Kanellias, View ORCID ProfileVille J. Kujala, View ORCID ProfileGauri Kulkarni, Christopher Y. Le, View ORCID ProfileCarolina Lucchesi, View ORCID ProfileDimitris V. Manatakis, Kairav K. Maniar, Meaghan E. Quinn, View ORCID ProfileJoseph S. Ravan, Ann Catherine Rizos, John F.K. Sauld, Josiah D. Sliz, William Tien-Street, Dennis Ramos Trinidad, James Velez, Max Wendell, Onyi Irrechukwu, View ORCID ProfilePrathap Kumar Mahalingaiah, View ORCID ProfileDonald E. Ingber, Jack W. Scannell, Daniel Levner
doi: https://doi.org/10.1101/2021.12.14.472674
Lorna Ewart
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Athanasia Apostolou
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Skyler A. Briggs
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Christopher V. Carman
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Jake T. Chaff
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Anthony R. Heng
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Sushma Jadalannagari
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Jeshina Janardhanan
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Kyung-Jin Jang
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Sannidhi R. Joshipura
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Mahika M. Kadam
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Marianne Kanellias
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Ville J. Kujala
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Gauri Kulkarni
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Christopher Y. Le
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Carolina Lucchesi
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Dimitris V. Manatakis
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Kairav K. Maniar
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Meaghan E. Quinn
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Joseph S. Ravan
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Ann Catherine Rizos
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
John F.K. Sauld
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Josiah D. Sliz
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
William Tien-Street
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Dennis Ramos Trinidad
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
James Velez
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Max Wendell
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Onyi Irrechukwu
2Janssen Pharmaceuticals, Spring House, Philadelphia, PA, United States
Prathap Kumar Mahalingaiah
3Investigative Toxicology and Pathology, Abbvie, North Chicago, IL, United States
Donald E. Ingber
4Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, United States
5Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, United States
6Vascular Biology Program and Department of Surgery, Harvard Medical School and Boston Children’s Hospital, Boston, MA, United States
Jack W. Scannell
7JW Scannell Analytics LTD, 32 Queens Crescent, Edinburgh, EH9 2BA, United Kingdom
Daniel Levner
1Emulate Inc., 27 Drydock Avenue, Boston, MA, United States
Posted August 02, 2022.
Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications
Lorna Ewart, Athanasia Apostolou, Skyler A. Briggs, Christopher V. Carman, Jake T. Chaff, Anthony R. Heng, Sushma Jadalannagari, Jeshina Janardhanan, Kyung-Jin Jang, Sannidhi R. Joshipura, Mahika M. Kadam, Marianne Kanellias, Ville J. Kujala, Gauri Kulkarni, Christopher Y. Le, Carolina Lucchesi, Dimitris V. Manatakis, Kairav K. Maniar, Meaghan E. Quinn, Joseph S. Ravan, Ann Catherine Rizos, John F.K. Sauld, Josiah D. Sliz, William Tien-Street, Dennis Ramos Trinidad, James Velez, Max Wendell, Onyi Irrechukwu, Prathap Kumar Mahalingaiah, Donald E. Ingber, Jack W. Scannell, Daniel Levner
bioRxiv 2021.12.14.472674; doi: https://doi.org/10.1101/2021.12.14.472674
Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications
Lorna Ewart, Athanasia Apostolou, Skyler A. Briggs, Christopher V. Carman, Jake T. Chaff, Anthony R. Heng, Sushma Jadalannagari, Jeshina Janardhanan, Kyung-Jin Jang, Sannidhi R. Joshipura, Mahika M. Kadam, Marianne Kanellias, Ville J. Kujala, Gauri Kulkarni, Christopher Y. Le, Carolina Lucchesi, Dimitris V. Manatakis, Kairav K. Maniar, Meaghan E. Quinn, Joseph S. Ravan, Ann Catherine Rizos, John F.K. Sauld, Josiah D. Sliz, William Tien-Street, Dennis Ramos Trinidad, James Velez, Max Wendell, Onyi Irrechukwu, Prathap Kumar Mahalingaiah, Donald E. Ingber, Jack W. Scannell, Daniel Levner
bioRxiv 2021.12.14.472674; doi: https://doi.org/10.1101/2021.12.14.472674
Subject Area
Subject Areas
- Biochemistry (11745)
- Bioengineering (8752)
- Bioinformatics (29200)
- Biophysics (14972)
- Cancer Biology (12096)
- Cell Biology (17411)
- Clinical Trials (138)
- Developmental Biology (9421)
- Ecology (14182)
- Epidemiology (2067)
- Evolutionary Biology (18308)
- Genetics (12245)
- Genomics (16803)
- Immunology (11869)
- Microbiology (28085)
- Molecular Biology (11592)
- Neuroscience (60969)
- Paleontology (451)
- Pathology (1871)
- Pharmacology and Toxicology (3238)
- Physiology (4959)
- Plant Biology (10427)
- Synthetic Biology (2885)
- Systems Biology (7340)
- Zoology (1651)