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Tryptophol acetate and tyrosol acetate, small molecule metabolites identified in a probiotic mixture, inhibit hyperinflammation
Orit Malka, Ravit Malishev, Marina Bersudsky, Manikandan Rajendran, Mathumathi Krishnamohan, Jakeer Shaik, Daniel A. Chamovitz, Evgeni Tikhonov, Eliya Sultan, Omry Koren, Ron N. Apte, Benyamin Rosental, Elena Voronov, View ORCID ProfileRaz Jelinek
doi: https://doi.org/10.1101/2021.12.16.472991
Orit Malka
1Department of Chemistry, Ben-Gurion University of the Negev, 84105 Be’er Sheva, Israel
Ravit Malishev
1Department of Chemistry, Ben-Gurion University of the Negev, 84105 Be’er Sheva, Israel
Marina Bersudsky
2Department of Microbiology and Immunology, Faculty of Health Sciences, The Cancer Research Center, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel
Manikandan Rajendran
1Department of Chemistry, Ben-Gurion University of the Negev, 84105 Be’er Sheva, Israel
Mathumathi Krishnamohan
2Department of Microbiology and Immunology, Faculty of Health Sciences, The Cancer Research Center, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel
Jakeer Shaik
2Department of Microbiology and Immunology, Faculty of Health Sciences, The Cancer Research Center, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel
Daniel A. Chamovitz
1Department of Chemistry, Ben-Gurion University of the Negev, 84105 Be’er Sheva, Israel
Evgeni Tikhonov
3The Azrieli Faculty of Medicine, Bar Ilan University, 1311502 Safed, Israel
Eliya Sultan
2Department of Microbiology and Immunology, Faculty of Health Sciences, The Cancer Research Center, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel
4Regenerative Medicine and Stem Cell Research Center, Ben-Gurion University of the Negev
Omry Koren
3The Azrieli Faculty of Medicine, Bar Ilan University, 1311502 Safed, Israel
Ron N. Apte
2Department of Microbiology and Immunology, Faculty of Health Sciences, The Cancer Research Center, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel
Benyamin Rosental
2Department of Microbiology and Immunology, Faculty of Health Sciences, The Cancer Research Center, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel
4Regenerative Medicine and Stem Cell Research Center, Ben-Gurion University of the Negev
Elena Voronov
2Department of Microbiology and Immunology, Faculty of Health Sciences, The Cancer Research Center, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel
Raz Jelinek
1Department of Chemistry, Ben-Gurion University of the Negev, 84105 Be’er Sheva, Israel
5Ilse Katz Institute for Nanoscale Science & Technology Ben Gurion University of the Negev, Be’er Sheva 84105, Israel
Posted October 29, 2022.
Tryptophol acetate and tyrosol acetate, small molecule metabolites identified in a probiotic mixture, inhibit hyperinflammation
Orit Malka, Ravit Malishev, Marina Bersudsky, Manikandan Rajendran, Mathumathi Krishnamohan, Jakeer Shaik, Daniel A. Chamovitz, Evgeni Tikhonov, Eliya Sultan, Omry Koren, Ron N. Apte, Benyamin Rosental, Elena Voronov, Raz Jelinek
bioRxiv 2021.12.16.472991; doi: https://doi.org/10.1101/2021.12.16.472991
Tryptophol acetate and tyrosol acetate, small molecule metabolites identified in a probiotic mixture, inhibit hyperinflammation
Orit Malka, Ravit Malishev, Marina Bersudsky, Manikandan Rajendran, Mathumathi Krishnamohan, Jakeer Shaik, Daniel A. Chamovitz, Evgeni Tikhonov, Eliya Sultan, Omry Koren, Ron N. Apte, Benyamin Rosental, Elena Voronov, Raz Jelinek
bioRxiv 2021.12.16.472991; doi: https://doi.org/10.1101/2021.12.16.472991
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