New Results
Overactive STAT3 drives accumulation of disease-associated CD21low B cells
View ORCID ProfileEtienne Masle-Farquhar, Timothy Peters, Katherine JL Jackson, Mandeep Singh, Cindy S Ma, Daniel Suan, Gulbu Uzel, Ignatius Chua, Jennifer W Leiding, Kaarina Heiskanen, Kahn Preece, Leena Kainulainen, Michael O’Sullivan, Megan A Cooper, Mikko RJ Seppänen, Satu Mustjoki, Shannon Brothers, Tiphanie P Vogel, Robert Brink, Stuart G Tangye, Joanne H Reed, Christopher C Goodnow
doi: https://doi.org/10.1101/2021.12.20.473595
Etienne Masle-Farquhar
1The Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia
2St Vincent’s Clinical School, UNSW Sydney, 2052, Australia
Timothy Peters
1The Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia
2St Vincent’s Clinical School, UNSW Sydney, 2052, Australia
Katherine JL Jackson
1The Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia
2St Vincent’s Clinical School, UNSW Sydney, 2052, Australia
Mandeep Singh
1The Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia
2St Vincent’s Clinical School, UNSW Sydney, 2052, Australia
Cindy S Ma
1The Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia
2St Vincent’s Clinical School, UNSW Sydney, 2052, Australia
Daniel Suan
3Westmead Clinical School, The University of Sydney, Westmead, NSW, Australia
Gulbu Uzel
4Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda
Ignatius Chua
5Canterbury Health Laboratories, Christchurch, New Zealand
Jennifer W Leiding
6Division of Allergy and Immunology, Department of Pediatrics, University of South Florida, Tampa, FL, USA
7Division of Allergy and Immunology, Johns Hopkins All Children’s Hospital, St. Petersburg, FL, USA
Kaarina Heiskanen
8Childreńs Immunodeficiency Unit, Hospital for Children and Adolescents, and Pediatric Research Center, Helsinki University Hospital and University of Helsinki, Finland
Kahn Preece
9Department of Pediatrics, Christchurch Hospital, Christchurch, New Zealand
Leena Kainulainen
10Department of Pediatrics, Turku University Hospital, University of Turku, Turku Finland
Michael O’Sullivan
11Immunology Department, Fiona Stanley Hospital, Murdoch, Australia
Megan A Cooper
12Department of Pedatrics, Division of Rheumatology/Immunology, Washington University School of Medicine, St. Louis, Missouri, USA
Mikko RJ Seppänen
13Rare Disease and Pediatric Research Centers, Hospital for Children and Adolescents, Helsinki University Hospital and University of Helsinki, Finland
Satu Mustjoki
14Translational Immunology Research Program and Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland
Shannon Brothers
15Starship Children’s Hospital, Auckland, New Zealand
Tiphanie P Vogel
12Department of Pedatrics, Division of Rheumatology/Immunology, Washington University School of Medicine, St. Louis, Missouri, USA
Robert Brink
1The Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia
2St Vincent’s Clinical School, UNSW Sydney, 2052, Australia
Stuart G Tangye
1The Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia
2St Vincent’s Clinical School, UNSW Sydney, 2052, Australia
Joanne H Reed
1The Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia
2St Vincent’s Clinical School, UNSW Sydney, 2052, Australia
Christopher C Goodnow
1The Garvan Institute of Medical Research, Darlinghurst, Sydney, NSW 2010, Australia
16Cellular Genomics Futures Institute, UNSW Sydney, Australia
Article usage
Posted December 21, 2021.
Overactive STAT3 drives accumulation of disease-associated CD21low B cells
Etienne Masle-Farquhar, Timothy Peters, Katherine JL Jackson, Mandeep Singh, Cindy S Ma, Daniel Suan, Gulbu Uzel, Ignatius Chua, Jennifer W Leiding, Kaarina Heiskanen, Kahn Preece, Leena Kainulainen, Michael O’Sullivan, Megan A Cooper, Mikko RJ Seppänen, Satu Mustjoki, Shannon Brothers, Tiphanie P Vogel, Robert Brink, Stuart G Tangye, Joanne H Reed, Christopher C Goodnow
bioRxiv 2021.12.20.473595; doi: https://doi.org/10.1101/2021.12.20.473595
Overactive STAT3 drives accumulation of disease-associated CD21low B cells
Etienne Masle-Farquhar, Timothy Peters, Katherine JL Jackson, Mandeep Singh, Cindy S Ma, Daniel Suan, Gulbu Uzel, Ignatius Chua, Jennifer W Leiding, Kaarina Heiskanen, Kahn Preece, Leena Kainulainen, Michael O’Sullivan, Megan A Cooper, Mikko RJ Seppänen, Satu Mustjoki, Shannon Brothers, Tiphanie P Vogel, Robert Brink, Stuart G Tangye, Joanne H Reed, Christopher C Goodnow
bioRxiv 2021.12.20.473595; doi: https://doi.org/10.1101/2021.12.20.473595
Subject Area
Subject Areas
- Biochemistry (11745)
- Bioengineering (8752)
- Bioinformatics (29200)
- Biophysics (14972)
- Cancer Biology (12096)
- Cell Biology (17411)
- Clinical Trials (138)
- Developmental Biology (9421)
- Ecology (14182)
- Epidemiology (2067)
- Evolutionary Biology (18308)
- Genetics (12245)
- Genomics (16803)
- Immunology (11869)
- Microbiology (28085)
- Molecular Biology (11592)
- Neuroscience (60969)
- Paleontology (451)
- Pathology (1871)
- Pharmacology and Toxicology (3238)
- Physiology (4959)
- Plant Biology (10427)
- Synthetic Biology (2885)
- Systems Biology (7340)
- Zoology (1651)