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BRPF3 knockdown or inhibition moderately reverses olaparib resistance in high grade serous ovarian carcinoma, but depletion of H3K14 acetylation has no effect

View ORCID ProfileBenjamin G. Bitler, Tomomi M. Yamamoto, Alexandra McMellen, Hyunmin Kim, Zachary L. Watson
doi: https://doi.org/10.1101/2021.12.21.473688
Benjamin G. Bitler
1Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, CO 80045, USA
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  • ORCID record for Benjamin G. Bitler
Tomomi M. Yamamoto
1Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, CO 80045, USA
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Alexandra McMellen
2Cancer Biology Graduate Program, University of Colorado, Aurora, CO 80045, USA
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Hyunmin Kim
3Translational Bioinformatics and Cancer Systems Biology Laboratory, Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
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Zachary L. Watson
1Division of Reproductive Sciences, Department of Obstetrics and Gynecology, University of Colorado School of Medicine, Aurora, CO 80045, USA
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  • For correspondence: zachary.watson@cuanschutz.edu
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Posted December 22, 2021.
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BRPF3 knockdown or inhibition moderately reverses olaparib resistance in high grade serous ovarian carcinoma, but depletion of H3K14 acetylation has no effect
Benjamin G. Bitler, Tomomi M. Yamamoto, Alexandra McMellen, Hyunmin Kim, Zachary L. Watson
bioRxiv 2021.12.21.473688; doi: https://doi.org/10.1101/2021.12.21.473688
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BRPF3 knockdown or inhibition moderately reverses olaparib resistance in high grade serous ovarian carcinoma, but depletion of H3K14 acetylation has no effect
Benjamin G. Bitler, Tomomi M. Yamamoto, Alexandra McMellen, Hyunmin Kim, Zachary L. Watson
bioRxiv 2021.12.21.473688; doi: https://doi.org/10.1101/2021.12.21.473688

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