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SARS-CoV-2 Omicron-B.1.1.529 Variant leads to less severe disease than Pango B and Delta variants strains in a mouse model of severe COVID-19
Eleanor G. Bentley, Adam Kirby, Parul Sharma, Anja Kipar, Daniele F. Mega, Chloe Bramwell, Rebekah Penrice-Randal, Tessa Prince, Jonathan C. Brown, Jie Zhou, Gavin R. Screaton, Wendy S. Barclay, Andrew Owen, Julian A. Hiscox, View ORCID ProfileJames P. Stewart
doi: https://doi.org/10.1101/2021.12.26.474085
Eleanor G. Bentley
1Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, UK
Adam Kirby
1Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, UK
Parul Sharma
1Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, UK
Anja Kipar
1Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, UK
2Laboratory for Animal Model Pathology, Institute of Veterinary Pathology, University of Zurich, Switzerland
Daniele F. Mega
1Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, UK
Chloe Bramwell
1Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, UK
Rebekah Penrice-Randal
1Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, UK
Tessa Prince
1Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, UK
Jonathan C. Brown
3Department of Infectious Disease, Imperial College London, London, UK
Jie Zhou
3Department of Infectious Disease, Imperial College London, London, UK
Gavin R. Screaton
4Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK
Wendy S. Barclay
3Department of Infectious Disease, Imperial College London, London, UK
Andrew Owen
5Department of Pharmacology and Therapeutics, Centre of Excellence in Long-acting Therapeutics (CELT), University of Liverpool, UK
Julian A. Hiscox
1Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, UK
6Department of Preventive Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China
7Infectious Diseases Horizontal Technology Centre (ID HTC), A*STAR, Singapore
James P. Stewart
1Department of Infection Biology & Microbiomes, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, UK
6Department of Preventive Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China
8Department of Infectious Disease, University of Georgia, Georgia, USA

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Posted December 30, 2021.
SARS-CoV-2 Omicron-B.1.1.529 Variant leads to less severe disease than Pango B and Delta variants strains in a mouse model of severe COVID-19
Eleanor G. Bentley, Adam Kirby, Parul Sharma, Anja Kipar, Daniele F. Mega, Chloe Bramwell, Rebekah Penrice-Randal, Tessa Prince, Jonathan C. Brown, Jie Zhou, Gavin R. Screaton, Wendy S. Barclay, Andrew Owen, Julian A. Hiscox, James P. Stewart
bioRxiv 2021.12.26.474085; doi: https://doi.org/10.1101/2021.12.26.474085
SARS-CoV-2 Omicron-B.1.1.529 Variant leads to less severe disease than Pango B and Delta variants strains in a mouse model of severe COVID-19
Eleanor G. Bentley, Adam Kirby, Parul Sharma, Anja Kipar, Daniele F. Mega, Chloe Bramwell, Rebekah Penrice-Randal, Tessa Prince, Jonathan C. Brown, Jie Zhou, Gavin R. Screaton, Wendy S. Barclay, Andrew Owen, Julian A. Hiscox, James P. Stewart
bioRxiv 2021.12.26.474085; doi: https://doi.org/10.1101/2021.12.26.474085
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