OTUD1 deubiquitylase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways

Daisuke Oikawa; Min Gi; Hidetaka Kosako; Kouhei Shimizu; Hirotaka Takahashi; Masayuki Shiota; Shuhei Hosomi; Keidai Komakura; Hideki Wanibuchi; Daisuke Tsuruta; Tatsuya Sawasaki; Fuminori Tokunaga

doi:10.1101/2021.12.26.474226

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OTUD1 deubiquitylase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways

Daisuke Oikawa, Min Gi, Hidetaka Kosako, Kouhei Shimizu, Hirotaka Takahashi, Masayuki Shiota, Shuhei Hosomi, Keidai Komakura, Hideki Wanibuchi, Daisuke Tsuruta, Tatsuya Sawasaki, View ORCID ProfileFuminori Tokunaga

doi: https://doi.org/10.1101/2021.12.26.474226

Daisuke Oikawa

1Department of Pathobiochemistry, Graduate School of Medicine, Osaka City University, Osaka, Japan.

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Min Gi

2Department of Environmental Risk Assessment, Graduate School of Medicine, Osaka City University, Osaka, Japan.

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Hidetaka Kosako

3Division of Cell Signaling, Fujii Memorial Institute of Medical Sciences, Tokushima University, Tokushima, Japan.

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Kouhei Shimizu

1Department of Pathobiochemistry, Graduate School of Medicine, Osaka City University, Osaka, Japan.

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Hirotaka Takahashi

4Division of Cell-Free Sciences, Proteo-Science Center (PROS), Ehime University, Japan.

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Masayuki Shiota

5Department of Molecular Biology of Cell, Graduate School of Medicine, Osaka City University, Osaka, Japan.

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Shuhei Hosomi

6Department of Gastroenterology, Graduate School of Medicine, Osaka City University, Osaka, Japan.

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Keidai Komakura

1Department of Pathobiochemistry, Graduate School of Medicine, Osaka City University, Osaka, Japan.

7Department of Dermatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.

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Hideki Wanibuchi

8Department of Molecular Pathology, Graduate School of Medicine, Osaka City University, Osaka, Japan.

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Daisuke Tsuruta

7Department of Dermatology, Graduate School of Medicine, Osaka City University, Osaka, Japan.

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Tatsuya Sawasaki

4Division of Cell-Free Sciences, Proteo-Science Center (PROS), Ehime University, Japan.

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Fuminori Tokunaga

1Department of Pathobiochemistry, Graduate School of Medicine, Osaka City University, Osaka, Japan.

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ORCID record for Fuminori Tokunaga
For correspondence: ftokunaga@med.osaka-cu.ac.jp

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Posted December 27, 2021.

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OTUD1 deubiquitylase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways

Daisuke Oikawa, Min Gi, Hidetaka Kosako, Kouhei Shimizu, Hirotaka Takahashi, Masayuki Shiota, Shuhei Hosomi, Keidai Komakura, Hideki Wanibuchi, Daisuke Tsuruta, Tatsuya Sawasaki, Fuminori Tokunaga

bioRxiv 2021.12.26.474226; doi: https://doi.org/10.1101/2021.12.26.474226

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OTUD1 deubiquitylase regulates NF-κB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways

Daisuke Oikawa, Min Gi, Hidetaka Kosako, Kouhei Shimizu, Hirotaka Takahashi, Masayuki Shiota, Shuhei Hosomi, Keidai Komakura, Hideki Wanibuchi, Daisuke Tsuruta, Tatsuya Sawasaki, Fuminori Tokunaga

bioRxiv 2021.12.26.474226; doi: https://doi.org/10.1101/2021.12.26.474226

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