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The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures and efficiently uses the endosomal route of entry

View ORCID ProfileThomas P. Peacock, View ORCID ProfileJonathan C. Brown, View ORCID ProfileJie Zhou, View ORCID ProfileNazia Thakur, Joseph Newman, View ORCID ProfileRuthiran Kugathasan, Ksenia Sukhova, View ORCID ProfileMyrsini Kaforou, View ORCID ProfileDalan Bailey, View ORCID ProfileWendy S. Barclay
doi: https://doi.org/10.1101/2021.12.31.474653
Thomas P. Peacock
1Department of Infectious Disease, Imperial College London, UK, W2 1PG
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  • ORCID record for Thomas P. Peacock
Jonathan C. Brown
1Department of Infectious Disease, Imperial College London, UK, W2 1PG
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  • ORCID record for Jonathan C. Brown
Jie Zhou
1Department of Infectious Disease, Imperial College London, UK, W2 1PG
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Nazia Thakur
2The Pirbright Institute, Woking, Surrey, UK, GU24 0NF
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Joseph Newman
2The Pirbright Institute, Woking, Surrey, UK, GU24 0NF
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Ruthiran Kugathasan
1Department of Infectious Disease, Imperial College London, UK, W2 1PG
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  • ORCID record for Ruthiran Kugathasan
Ksenia Sukhova
1Department of Infectious Disease, Imperial College London, UK, W2 1PG
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Myrsini Kaforou
1Department of Infectious Disease, Imperial College London, UK, W2 1PG
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  • ORCID record for Myrsini Kaforou
Dalan Bailey
2The Pirbright Institute, Woking, Surrey, UK, GU24 0NF
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  • ORCID record for Dalan Bailey
Wendy S. Barclay
1Department of Infectious Disease, Imperial College London, UK, W2 1PG
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  • ORCID record for Wendy S. Barclay
  • For correspondence: w.barclay@imperial.ac.uk
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Article Information

doi 
https://doi.org/10.1101/2021.12.31.474653
History 
  • January 3, 2022.

Article Versions

  • You are currently viewing Version 1 of this article (January 3, 2022 - 17:12).
  • View Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.

Author Information

  1. Thomas P. Peacock1,#,
  2. Jonathan C. Brown1,#,
  3. Jie Zhou1,#,
  4. Nazia Thakur2,
  5. Joseph Newman2,
  6. Ruthiran Kugathasan1,
  7. Ksenia Sukhova1,
  8. Myrsini Kaforou1,
  9. Dalan Bailey2 and
  10. Wendy S. Barclay1,*
  1. 1Department of Infectious Disease, Imperial College London, UK, W2 1PG
  2. 2The Pirbright Institute, Woking, Surrey, UK, GU24 0NF
  1. ↵*Corresponding author: w.barclay{at}imperial.ac.uk
  1. ↵# These authors contributed equally to this work

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Posted January 03, 2022.
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The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures and efficiently uses the endosomal route of entry
Thomas P. Peacock, Jonathan C. Brown, Jie Zhou, Nazia Thakur, Joseph Newman, Ruthiran Kugathasan, Ksenia Sukhova, Myrsini Kaforou, Dalan Bailey, Wendy S. Barclay
bioRxiv 2021.12.31.474653; doi: https://doi.org/10.1101/2021.12.31.474653
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The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures and efficiently uses the endosomal route of entry
Thomas P. Peacock, Jonathan C. Brown, Jie Zhou, Nazia Thakur, Joseph Newman, Ruthiran Kugathasan, Ksenia Sukhova, Myrsini Kaforou, Dalan Bailey, Wendy S. Barclay
bioRxiv 2021.12.31.474653; doi: https://doi.org/10.1101/2021.12.31.474653

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