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Cross-talk between cAMP and Ca2+ signalling in cardiac pacemaker cells involves IP3-evoked Ca2+ release and stimulation of adenylyl cyclase 1

View ORCID ProfileSamuel J. Bose, Matthew Read, Rebecca A Capel, Emily Akerman, Thamali Ayagama, Angela Russell, Derek A Terrar, Manuela Zaccolo, Rebecca AB Burton
doi: https://doi.org/10.1101/2022.01.06.475211
Samuel J. Bose
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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  • ORCID record for Samuel J. Bose
Matthew Read
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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Rebecca A Capel
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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Emily Akerman
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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Thamali Ayagama
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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Angela Russell
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
2Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK
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Derek A Terrar
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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Manuela Zaccolo
3Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, OX1 3PT
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Rebecca AB Burton
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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  • For correspondence: rebecca.burton@pharm.ox.ac.uk
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Article Information

doi 
https://doi.org/10.1101/2022.01.06.475211
History 
  • January 6, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Samuel J. Bose1,
  2. Matthew Read1,
  3. Rebecca A Capel1,
  4. Emily Akerman1,
  5. Thamali Ayagama1,
  6. Angela Russell1,2,
  7. Derek A Terrar1,
  8. Manuela Zaccolo3 and
  9. Rebecca AB Burton1,*
  1. 1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
  2. 2Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK
  3. 3Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, OX1 3PT
  1. ↵*Correspondence to:
    Dr Rebecca-Ann B Burton, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, Oxon, OX1 3QT. rebecca.burton{at}pharm.ox.ac.uk
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Posted January 06, 2022.
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Cross-talk between cAMP and Ca2+ signalling in cardiac pacemaker cells involves IP3-evoked Ca2+ release and stimulation of adenylyl cyclase 1
Samuel J. Bose, Matthew Read, Rebecca A Capel, Emily Akerman, Thamali Ayagama, Angela Russell, Derek A Terrar, Manuela Zaccolo, Rebecca AB Burton
bioRxiv 2022.01.06.475211; doi: https://doi.org/10.1101/2022.01.06.475211
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Cross-talk between cAMP and Ca2+ signalling in cardiac pacemaker cells involves IP3-evoked Ca2+ release and stimulation of adenylyl cyclase 1
Samuel J. Bose, Matthew Read, Rebecca A Capel, Emily Akerman, Thamali Ayagama, Angela Russell, Derek A Terrar, Manuela Zaccolo, Rebecca AB Burton
bioRxiv 2022.01.06.475211; doi: https://doi.org/10.1101/2022.01.06.475211

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