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Cross-talk between cAMP and Ca2+ signalling in cardiac pacemaker cells involves IP3-evoked Ca2+ release and stimulation of adenylyl cyclase 1

View ORCID ProfileSamuel J. Bose, Matthew Read, Rebecca A Capel, Emily Akerman, Thamali Ayagama, Angela Russell, Derek A Terrar, Manuela Zaccolo, Rebecca AB Burton
doi: https://doi.org/10.1101/2022.01.06.475211
Samuel J. Bose
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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  • ORCID record for Samuel J. Bose
Matthew Read
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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Rebecca A Capel
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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Emily Akerman
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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Thamali Ayagama
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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Angela Russell
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
2Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK
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Derek A Terrar
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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Manuela Zaccolo
3Department of Physiology, Anatomy and Genetics, University of Oxford, Parks Road, OX1 3PT
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Rebecca AB Burton
1Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT
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  • For correspondence: rebecca.burton@pharm.ox.ac.uk
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Posted January 06, 2022.
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Cross-talk between cAMP and Ca2+ signalling in cardiac pacemaker cells involves IP3-evoked Ca2+ release and stimulation of adenylyl cyclase 1
Samuel J. Bose, Matthew Read, Rebecca A Capel, Emily Akerman, Thamali Ayagama, Angela Russell, Derek A Terrar, Manuela Zaccolo, Rebecca AB Burton
bioRxiv 2022.01.06.475211; doi: https://doi.org/10.1101/2022.01.06.475211
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Cross-talk between cAMP and Ca2+ signalling in cardiac pacemaker cells involves IP3-evoked Ca2+ release and stimulation of adenylyl cyclase 1
Samuel J. Bose, Matthew Read, Rebecca A Capel, Emily Akerman, Thamali Ayagama, Angela Russell, Derek A Terrar, Manuela Zaccolo, Rebecca AB Burton
bioRxiv 2022.01.06.475211; doi: https://doi.org/10.1101/2022.01.06.475211

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