New Results
Genetic Impairment of Succinate Metabolism Disrupts Bioenergetic Sensing in Adrenal Neuroendocrine Cancer
Priyanka Gupta, Keehn Strange, Rahul Telange, Ailan Guo, Heather Hatch, Amin Sobh, Jonathan Elie, Angela M. Carter, John Totenhagen, Chunfeng Tan, Yogesh A. Sonawane, Jiri Neuzil, Amarnath Natarajan, Ashley J. Ovens, Jonathan S. Oakhill, Thorsten Wiederhold, Karel Pacak, Hans K. Ghayee, Laurent Meijer, Sushanth Reddy, James A. Bibb
doi: https://doi.org/10.1101/2022.01.09.475410
Priyanka Gupta
1Department of Surgery, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35233, USA
Keehn Strange
1Department of Surgery, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35233, USA
Rahul Telange
2Department of Hematology, St Jude Children’s Research Hospital, Memphis, TN 38105, USA
Ailan Guo
3Cell Signaling Technology, Danvers, MA 01923, USA
Heather Hatch
4Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
Amin Sobh
5Department of Medicine, Division of Hematology and Oncology, University of Florida Gainesville, FL 32608, USA
Jonathan Elie
6Perha Pharmaceuticals, Hôtel de Recherche, Perharidy Peninsula, 29680 Roscoff, France.
Angela M. Carter
1Department of Surgery, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35233, USA
John Totenhagen
7Department of Radiology, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35233, USA
Chunfeng Tan
8Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390,USA
Yogesh A. Sonawane
9Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE 68198
Jiri Neuzil
10Institute of Biotechnology, Czech Academy of Sciences, Prague-West 252 50, Czech Republic
11School of Pharmacy Medical Science, Griffith University, Southport, Qld 4222, Australia
Amarnath Natarajan
9Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE 68198
Ashley J. Ovens
12Metabolic Signalling Laboratory, St Vincent’s Institute of Medical Research, Fitzroy, Victoria, Australia
13Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia
Jonathan S. Oakhill
12Metabolic Signalling Laboratory, St Vincent’s Institute of Medical Research, Fitzroy, Victoria, Australia
13Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria, Australia
Thorsten Wiederhold
3Cell Signaling Technology, Danvers, MA 01923, USA
Karel Pacak
14Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and 23 Human Development, National Institutes of Health, Bethesda, MD 20892, USA
Hans K. Ghayee
15Department of Internal Medicine, Division of Endocrinology, University of Florida College of Medicine and Malcom Randall VA Medical Center, Gainesville, FL 32608, USA
Laurent Meijer
6Perha Pharmaceuticals, Hôtel de Recherche, Perharidy Peninsula, 29680 Roscoff, France.
Sushanth Reddy
1Department of Surgery, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35233, USA
James A. Bibb
1Department of Surgery, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35233, USA
16O’Neal Comprehensive Cancer Center and the Department of Neurobiology, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35233, USA
Article usage
Posted January 10, 2022.
Genetic Impairment of Succinate Metabolism Disrupts Bioenergetic Sensing in Adrenal Neuroendocrine Cancer
Priyanka Gupta, Keehn Strange, Rahul Telange, Ailan Guo, Heather Hatch, Amin Sobh, Jonathan Elie, Angela M. Carter, John Totenhagen, Chunfeng Tan, Yogesh A. Sonawane, Jiri Neuzil, Amarnath Natarajan, Ashley J. Ovens, Jonathan S. Oakhill, Thorsten Wiederhold, Karel Pacak, Hans K. Ghayee, Laurent Meijer, Sushanth Reddy, James A. Bibb
bioRxiv 2022.01.09.475410; doi: https://doi.org/10.1101/2022.01.09.475410
Genetic Impairment of Succinate Metabolism Disrupts Bioenergetic Sensing in Adrenal Neuroendocrine Cancer
Priyanka Gupta, Keehn Strange, Rahul Telange, Ailan Guo, Heather Hatch, Amin Sobh, Jonathan Elie, Angela M. Carter, John Totenhagen, Chunfeng Tan, Yogesh A. Sonawane, Jiri Neuzil, Amarnath Natarajan, Ashley J. Ovens, Jonathan S. Oakhill, Thorsten Wiederhold, Karel Pacak, Hans K. Ghayee, Laurent Meijer, Sushanth Reddy, James A. Bibb
bioRxiv 2022.01.09.475410; doi: https://doi.org/10.1101/2022.01.09.475410
Subject Area
Subject Areas
- Biochemistry (11753)
- Bioengineering (8752)
- Bioinformatics (29201)
- Biophysics (14974)
- Cancer Biology (12100)
- Cell Biology (17413)
- Clinical Trials (138)
- Developmental Biology (9422)
- Ecology (14182)
- Epidemiology (2067)
- Evolutionary Biology (18309)
- Genetics (12245)
- Genomics (16804)
- Immunology (11869)
- Microbiology (28098)
- Molecular Biology (11596)
- Neuroscience (60975)
- Paleontology (451)
- Pathology (1871)
- Pharmacology and Toxicology (3238)
- Physiology (4959)
- Plant Biology (10427)
- Synthetic Biology (2886)
- Systems Biology (7340)
- Zoology (1651)