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Identification of a phage display-derived peptide interacting with the N-terminal region of Factor VII activating protease (FSAP) enables characterization of zymogen activation

Sebastian Seidl, Nis Valentin Nielsen, Michael Escheid, Bengt Erik Haug, Maria Stensland, Bernd Thiede, Paul J. Declerck, Geir Åge Løset, Sandip M. Kanse
doi: https://doi.org/10.1101/2022.01.09.475526
Sebastian Seidl
1Oslo University Hospital and Medical Faculty, University of Oslo, Oslo, Norway
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Nis Valentin Nielsen
1Oslo University Hospital and Medical Faculty, University of Oslo, Oslo, Norway
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Michael Escheid
2Paul Ehrlich Institute, Langen, Germany
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Bengt Erik Haug
3Department of Chemistry and Center for Pharmacy, University of Bergen, Bergen, Norway
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Maria Stensland
1Oslo University Hospital and Medical Faculty, University of Oslo, Oslo, Norway
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Bernd Thiede
4Department of Biosciences, University of Oslo, Oslo, Norway
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Paul J. Declerck
5Department of Pharmaceutical and Pharmacological Sciences, Katholieke Universiteit Leuven, Belgium
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Geir Åge Løset
1Oslo University Hospital and Medical Faculty, University of Oslo, Oslo, Norway
6Nextera, Oslo, Norway
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Sandip M. Kanse
1Oslo University Hospital and Medical Faculty, University of Oslo, Oslo, Norway
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  • For correspondence: sandip.kanse@medisin.uio.no
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Article Information

doi 
https://doi.org/10.1101/2022.01.09.475526
History 
  • January 9, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Sebastian Seidl1,#,
  2. Nis Valentin Nielsen1,#,
  3. Michael Escheid2,
  4. Bengt Erik Haug3,
  5. Maria Stensland1,
  6. Bernd Thiede4,
  7. Paul J. Declerck5,
  8. Geir Åge Løset1,6 and
  9. Sandip M. Kanse1,*
  1. 1Oslo University Hospital and Medical Faculty, University of Oslo, Oslo, Norway
  2. 2Paul Ehrlich Institute, Langen, Germany
  3. 3Department of Chemistry and Center for Pharmacy, University of Bergen, Bergen, Norway
  4. 4Department of Biosciences, University of Oslo, Oslo, Norway
  5. 5Department of Pharmaceutical and Pharmacological Sciences, Katholieke Universiteit Leuven, Belgium
  6. 6Nextera, Oslo, Norway
  1. ↵*Correspondence:
    Sandip M. Kanse, Institute for Basic Medical Sciences, University of Oslo, 0172, Oslo, Norway. E-mail: sandip.kanse{at}medisin.uio.no
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Posted January 09, 2022.
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Identification of a phage display-derived peptide interacting with the N-terminal region of Factor VII activating protease (FSAP) enables characterization of zymogen activation
Sebastian Seidl, Nis Valentin Nielsen, Michael Escheid, Bengt Erik Haug, Maria Stensland, Bernd Thiede, Paul J. Declerck, Geir Åge Løset, Sandip M. Kanse
bioRxiv 2022.01.09.475526; doi: https://doi.org/10.1101/2022.01.09.475526
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Identification of a phage display-derived peptide interacting with the N-terminal region of Factor VII activating protease (FSAP) enables characterization of zymogen activation
Sebastian Seidl, Nis Valentin Nielsen, Michael Escheid, Bengt Erik Haug, Maria Stensland, Bernd Thiede, Paul J. Declerck, Geir Åge Løset, Sandip M. Kanse
bioRxiv 2022.01.09.475526; doi: https://doi.org/10.1101/2022.01.09.475526

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