Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer’s disease

Chirag Gupta, Jielin Xu, Ting Jin, Saniya Khullar, Xiaoyu Liu, Sayali Alatkar, Feixiong Cheng, View ORCID ProfileDaifeng Wang
doi: https://doi.org/10.1101/2022.01.09.475548
Chirag Gupta
1Waisman Center, University of Wisconsin-Madison, Madison, WI, 53705, USA
2Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53076, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jielin Xu
3Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ting Jin
1Waisman Center, University of Wisconsin-Madison, Madison, WI, 53705, USA
2Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53076, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Saniya Khullar
1Waisman Center, University of Wisconsin-Madison, Madison, WI, 53705, USA
2Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53076, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Xiaoyu Liu
4Department of Statistics, University of Wisconsin-Madison, Madison, WI 53076, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sayali Alatkar
1Waisman Center, University of Wisconsin-Madison, Madison, WI, 53705, USA
5Department of Computer Sciences, University of Wisconsin-Madison, Madison, WI 53076, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Feixiong Cheng
3Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
6Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44195, USA
7Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Daifeng Wang
1Waisman Center, University of Wisconsin-Madison, Madison, WI, 53705, USA
2Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53076, USA
5Department of Computer Sciences, University of Wisconsin-Madison, Madison, WI 53076, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Daifeng Wang
  • For correspondence: daifeng.wang@wisc.edu
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Preview PDF
Loading

Article Information

doi 
https://doi.org/10.1101/2022.01.09.475548
History 
  • January 11, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Chirag Gupta1,2,
  2. Jielin Xu3,
  3. Ting Jin1,2,
  4. Saniya Khullar1,2,
  5. Xiaoyu Liu4,
  6. Sayali Alatkar1,5,
  7. Feixiong Cheng3,6,7 and
  8. Daifeng Wang1,2,5,*
  1. 1Waisman Center, University of Wisconsin-Madison, Madison, WI, 53705, USA
  2. 2Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53076, USA
  3. 3Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
  4. 4Department of Statistics, University of Wisconsin-Madison, Madison, WI 53076, USA
  5. 5Department of Computer Sciences, University of Wisconsin-Madison, Madison, WI 53076, USA
  6. 6Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44195, USA
  7. 7Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
  1. ↵*Corresponding author: daifeng.wang{at}wisc.edu
Back to top
PreviousNext
Posted January 11, 2022.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer’s disease
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer’s disease
Chirag Gupta, Jielin Xu, Ting Jin, Saniya Khullar, Xiaoyu Liu, Sayali Alatkar, Feixiong Cheng, Daifeng Wang
bioRxiv 2022.01.09.475548; doi: https://doi.org/10.1101/2022.01.09.475548
Digg logo Reddit logo Twitter logo Facebook logo Google logo LinkedIn logo Mendeley logo
Citation Tools
Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer’s disease
Chirag Gupta, Jielin Xu, Ting Jin, Saniya Khullar, Xiaoyu Liu, Sayali Alatkar, Feixiong Cheng, Daifeng Wang
bioRxiv 2022.01.09.475548; doi: https://doi.org/10.1101/2022.01.09.475548

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Bioinformatics
Subject Areas
All Articles
  • Animal Behavior and Cognition (3482)
  • Biochemistry (7329)
  • Bioengineering (5301)
  • Bioinformatics (20212)
  • Biophysics (9985)
  • Cancer Biology (7706)
  • Cell Biology (11273)
  • Clinical Trials (138)
  • Developmental Biology (6425)
  • Ecology (9923)
  • Epidemiology (2065)
  • Evolutionary Biology (13292)
  • Genetics (9353)
  • Genomics (12559)
  • Immunology (7681)
  • Microbiology (18964)
  • Molecular Biology (7421)
  • Neuroscience (40915)
  • Paleontology (298)
  • Pathology (1226)
  • Pharmacology and Toxicology (2130)
  • Physiology (3145)
  • Plant Biology (6842)
  • Scientific Communication and Education (1271)
  • Synthetic Biology (1893)
  • Systems Biology (5299)
  • Zoology (1086)