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A novel structure-based approach for identification of vertebrate susceptibility to SARS-CoV-2: implications for future surveillance programmes

Rahul Kaushik, Naveen Kumar, Kam Y. J. Zhang, Pratiksha Srivastava, Sandeep Bhatia, Yashpal Singh Malik
doi: https://doi.org/10.1101/2022.01.10.475752
Rahul Kaushik
1Laboratory for Structural Bioinformatics, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Yokohama, Kanagawa 230-0045, Japan
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Naveen Kumar
2Zoonotic Diseases Group, ICAR-National Institute of High Security Animal Diseases, Bhopal 462022, India
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Kam Y. J. Zhang
1Laboratory for Structural Bioinformatics, Center for Biosystems Dynamics Research, RIKEN, 1-7-22 Suehiro, Yokohama, Kanagawa 230-0045, Japan
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Pratiksha Srivastava
2Zoonotic Diseases Group, ICAR-National Institute of High Security Animal Diseases, Bhopal 462022, India
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Sandeep Bhatia
2Zoonotic Diseases Group, ICAR-National Institute of High Security Animal Diseases, Bhopal 462022, India
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Yashpal Singh Malik
3College of Animal Biotechnology, Guru Angad Dev Veterinary and Animal Science University (GADVASU), Ludhiana 141004, Punjab, India
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  • For correspondence: malikyps@gmail.com
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  • The species-wise number of the ACE2 orthologs retrieved from the NCBI protein database are provided in Supplementary Table S1.[supplements/475752_file03.xlsx]
  • Supplementary Table S2 has more information on these protein complexes.[supplements/475752_file04.xlsx]
  • implemented in CPP4 software suite (Supplementary Table S3)[supplements/475752_file05.xlsx]
  • with sequence identities of 96.05-96.86% (Supplementary Table S4). However, the ACE2[supplements/475752_file06.xlsx]
  • The results for all the vertebrate species are provided in Supplementary Table S5[supplements/475752_file07.xlsx]
  • the rest of 8 bat species were predicted to be resistant to SARS-CoV-2 (Supplementary Table S6).[supplements/475752_file08.xlsx]
  • selected vertebrate species are provided in Supplementary Table S7.[supplements/475752_file09.xlsx]
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Posted January 12, 2022.
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A novel structure-based approach for identification of vertebrate susceptibility to SARS-CoV-2: implications for future surveillance programmes
Rahul Kaushik, Naveen Kumar, Kam Y. J. Zhang, Pratiksha Srivastava, Sandeep Bhatia, Yashpal Singh Malik
bioRxiv 2022.01.10.475752; doi: https://doi.org/10.1101/2022.01.10.475752
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A novel structure-based approach for identification of vertebrate susceptibility to SARS-CoV-2: implications for future surveillance programmes
Rahul Kaushik, Naveen Kumar, Kam Y. J. Zhang, Pratiksha Srivastava, Sandeep Bhatia, Yashpal Singh Malik
bioRxiv 2022.01.10.475752; doi: https://doi.org/10.1101/2022.01.10.475752

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