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Cross-linking of the Endolysosomal System Reveals Flotillin Structures and Putative Cargo

Jasjot Singh, Hadeer Elhabashy, Pathma Muthukottiappan, Markus Stepath, Martin Eisenacher, Oliver Kohlbacher, Volkmar Gieselmann, Dominic Winter
doi: https://doi.org/10.1101/2022.01.12.475930
Jasjot Singh
1Institute for Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
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  • For correspondence: jsin@uni-bonn.de dominic.winter@uni-bonn.de
Hadeer Elhabashy
2Department of Protein Evolution, Max-Planck-Institute for Developmental Biology, Max-Planck- Ring 5, 72076 Tübingen, Germany.
3Institute for Bioinformatics and Medical Informatics, University of Tübingen, Sand 14, 72076, Tübingen, Germany.
4Department of Computer Science, University of Tübingen, Sand 14, 72076 Tübingen, Germany.
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Pathma Muthukottiappan
1Institute for Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
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Markus Stepath
5Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, Bochum, Germany.
6Medical Proteome Analysis, Center for Protein Diagnostics, Ruhr-University Bochum, Bochum, Germany.
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Martin Eisenacher
5Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, Bochum, Germany.
6Medical Proteome Analysis, Center for Protein Diagnostics, Ruhr-University Bochum, Bochum, Germany.
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Oliver Kohlbacher
3Institute for Bioinformatics and Medical Informatics, University of Tübingen, Sand 14, 72076, Tübingen, Germany.
4Department of Computer Science, University of Tübingen, Sand 14, 72076 Tübingen, Germany.
7Institute for Translational Bioinformatics, University Hospital Tübingen, 72076 Tübingen, Germany.
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Volkmar Gieselmann
1Institute for Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
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Dominic Winter
1Institute for Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
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  • For correspondence: jsin@uni-bonn.de dominic.winter@uni-bonn.de
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Article Information

doi 
https://doi.org/10.1101/2022.01.12.475930
History 
  • January 12, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.

Author Information

  1. Jasjot Singh1,*,
  2. Hadeer Elhabashy2,3,4,
  3. Pathma Muthukottiappan1,
  4. Markus Stepath5,6,
  5. Martin Eisenacher5,6,
  6. Oliver Kohlbacher3,4,7,
  7. Volkmar Gieselmann1 and
  8. Dominic Winter1,8,*
  1. 1Institute for Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.
  2. 2Department of Protein Evolution, Max-Planck-Institute for Developmental Biology, Max-Planck- Ring 5, 72076 Tübingen, Germany.
  3. 3Institute for Bioinformatics and Medical Informatics, University of Tübingen, Sand 14, 72076, Tübingen, Germany.
  4. 4Department of Computer Science, University of Tübingen, Sand 14, 72076 Tübingen, Germany.
  5. 5Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, Bochum, Germany.
  6. 6Medical Proteome Analysis, Center for Protein Diagnostics, Ruhr-University Bochum, Bochum, Germany.
  7. 7Institute for Translational Bioinformatics, University Hospital Tübingen, 72076 Tübingen, Germany.
  1. ↵*Corresponding authors Jasjot Singh and Dr. Dominic Winter Institute for Biochemistry and Molecular Biology University of Bonn Nussallee 11, 53115 Bonn, Germany Email: jsin{at}uni-bonn.de; dominic.winter{at}uni-bonn.de
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Posted January 12, 2022.
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Cross-linking of the Endolysosomal System Reveals Flotillin Structures and Putative Cargo
Jasjot Singh, Hadeer Elhabashy, Pathma Muthukottiappan, Markus Stepath, Martin Eisenacher, Oliver Kohlbacher, Volkmar Gieselmann, Dominic Winter
bioRxiv 2022.01.12.475930; doi: https://doi.org/10.1101/2022.01.12.475930
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Cross-linking of the Endolysosomal System Reveals Flotillin Structures and Putative Cargo
Jasjot Singh, Hadeer Elhabashy, Pathma Muthukottiappan, Markus Stepath, Martin Eisenacher, Oliver Kohlbacher, Volkmar Gieselmann, Dominic Winter
bioRxiv 2022.01.12.475930; doi: https://doi.org/10.1101/2022.01.12.475930

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