Cross-linking of the Endolysosomal System Reveals Flotillin Structures and Putative Cargo

Jasjot Singh; Hadeer Elhabashy; Pathma Muthukottiappan; Markus Stepath; Martin Eisenacher; Oliver Kohlbacher; Volkmar Gieselmann; Dominic Winter

doi:10.1101/2022.01.12.475930

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Cross-linking of the Endolysosomal System Reveals Flotillin Structures and Putative Cargo

Jasjot Singh, Hadeer Elhabashy, Pathma Muthukottiappan, Markus Stepath, Martin Eisenacher, Oliver Kohlbacher, Volkmar Gieselmann, Dominic Winter

doi: https://doi.org/10.1101/2022.01.12.475930

Jasjot Singh

1Institute for Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.

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For correspondence: jsin@uni-bonn.de dominic.winter@uni-bonn.de

Hadeer Elhabashy

2Department of Protein Evolution, Max-Planck-Institute for Developmental Biology, Max-Planck- Ring 5, 72076 Tübingen, Germany.

3Institute for Bioinformatics and Medical Informatics, University of Tübingen, Sand 14, 72076, Tübingen, Germany.

4Department of Computer Science, University of Tübingen, Sand 14, 72076 Tübingen, Germany.

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Pathma Muthukottiappan

1Institute for Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.

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Markus Stepath

5Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, Bochum, Germany.

6Medical Proteome Analysis, Center for Protein Diagnostics, Ruhr-University Bochum, Bochum, Germany.

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Martin Eisenacher

5Medizinisches Proteom-Center, Medical Faculty, Ruhr-University Bochum, Bochum, Germany.

6Medical Proteome Analysis, Center for Protein Diagnostics, Ruhr-University Bochum, Bochum, Germany.

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Oliver Kohlbacher

3Institute for Bioinformatics and Medical Informatics, University of Tübingen, Sand 14, 72076, Tübingen, Germany.

4Department of Computer Science, University of Tübingen, Sand 14, 72076 Tübingen, Germany.

7Institute for Translational Bioinformatics, University Hospital Tübingen, 72076 Tübingen, Germany.

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Volkmar Gieselmann

1Institute for Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.

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Dominic Winter

1Institute for Biochemistry and Molecular Biology, Medical Faculty, University of Bonn, 53115 Bonn, Germany.

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For correspondence: jsin@uni-bonn.de dominic.winter@uni-bonn.de

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Cross-linking of the Endolysosomal System Reveals Flotillin Structures and Putative Cargo

Jasjot Singh, Hadeer Elhabashy, Pathma Muthukottiappan, Markus Stepath, Martin Eisenacher, Oliver Kohlbacher, Volkmar Gieselmann, Dominic Winter

bioRxiv 2022.01.12.475930; doi: https://doi.org/10.1101/2022.01.12.475930

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Cross-linking of the Endolysosomal System Reveals Flotillin Structures and Putative Cargo

Jasjot Singh, Hadeer Elhabashy, Pathma Muthukottiappan, Markus Stepath, Martin Eisenacher, Oliver Kohlbacher, Volkmar Gieselmann, Dominic Winter

bioRxiv 2022.01.12.475930; doi: https://doi.org/10.1101/2022.01.12.475930

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