New Results
Re-routing metabolism by the mitochondrial pyruvate carrier inhibitor MSDC-0160 attenuates neurodegeneration in a rat model of Parkinson’s disease
View ORCID ProfileDavid Mallet, Raphael Goutaudier, Emmanuel L. Barbier, Sebastien Carnicella, Jerry R. Colca, Florence Fauvelle, Sabrina Boulet
doi: https://doi.org/10.1101/2022.01.17.476616
David Mallet
1Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, 38000 Grenoble, France
Raphael Goutaudier
1Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, 38000 Grenoble, France
Emmanuel L. Barbier
1Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, 38000 Grenoble, France
3Université Grenoble Alpes, Inserm, US17, CNRS, UMS 3552, CHU Grenoble Alpes, IRMaGe, Grenoble, France
Sebastien Carnicella
1Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, 38000 Grenoble, France
Jerry R. Colca
2Metabolic Solutions Development Company, Kalamazoo, MI 49007, USA
Florence Fauvelle
1Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, 38000 Grenoble, France
3Université Grenoble Alpes, Inserm, US17, CNRS, UMS 3552, CHU Grenoble Alpes, IRMaGe, Grenoble, France
Sabrina Boulet
1Université Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, 38000 Grenoble, France
Posted January 20, 2022.
Re-routing metabolism by the mitochondrial pyruvate carrier inhibitor MSDC-0160 attenuates neurodegeneration in a rat model of Parkinson’s disease
David Mallet, Raphael Goutaudier, Emmanuel L. Barbier, Sebastien Carnicella, Jerry R. Colca, Florence Fauvelle, Sabrina Boulet
bioRxiv 2022.01.17.476616; doi: https://doi.org/10.1101/2022.01.17.476616
Re-routing metabolism by the mitochondrial pyruvate carrier inhibitor MSDC-0160 attenuates neurodegeneration in a rat model of Parkinson’s disease
David Mallet, Raphael Goutaudier, Emmanuel L. Barbier, Sebastien Carnicella, Jerry R. Colca, Florence Fauvelle, Sabrina Boulet
bioRxiv 2022.01.17.476616; doi: https://doi.org/10.1101/2022.01.17.476616
Subject Area
Subject Areas
- Biochemistry (12783)
- Bioengineering (9671)
- Bioinformatics (31250)
- Biophysics (16090)
- Cancer Biology (13175)
- Cell Biology (18846)
- Clinical Trials (138)
- Developmental Biology (10202)
- Ecology (15183)
- Epidemiology (2067)
- Evolutionary Biology (19394)
- Genetics (12880)
- Genomics (17772)
- Immunology (12899)
- Microbiology (30190)
- Molecular Biology (12605)
- Neuroscience (65885)
- Paleontology (486)
- Pathology (2041)
- Pharmacology and Toxicology (3517)
- Physiology (5446)
- Plant Biology (11283)
- Synthetic Biology (3122)
- Systems Biology (7764)
- Zoology (1756)