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Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes

View ORCID ProfileChan-Su Park, View ORCID ProfileJian Guan, Peter Rhee, Federico Gonzalez, View ORCID ProfileLaurent Coscoy, View ORCID ProfileEllen A. Robey, View ORCID ProfileNilabh Shastri, Scheherazade Sadegh-Nasseri
doi: https://doi.org/10.1101/2022.01.18.476719
Chan-Su Park
1Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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  • For correspondence: cpark52@jh.edu
Jian Guan
1Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Peter Rhee
1Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Federico Gonzalez
2Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA
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Laurent Coscoy
3Department of Molecular and Cell Biology, University of California, Berkeley, California, USA
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Ellen A. Robey
3Department of Molecular and Cell Biology, University of California, Berkeley, California, USA
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  • For correspondence: cpark52@jh.edu
Nilabh Shastri
1Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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  • For correspondence: cpark52@jh.edu
Scheherazade Sadegh-Nasseri
1Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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  • For correspondence: cpark52@jh.edu
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Article Information

doi 
https://doi.org/10.1101/2022.01.18.476719
History 
  • January 18, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Chan-Su Park1,*,
  2. Jian Guan1,
  3. Peter Rhee1,
  4. Federico Gonzalez2,
  5. Laurent Coscoy3,
  6. Ellen A. Robey3,*,
  7. Nilabh Shastri1,* and
  8. Scheherazade Sadegh-Nasseri1,*
  1. 1Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
  2. 2Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA
  3. 3Department of Molecular and Cell Biology, University of California, Berkeley, California, USA
  1. ↵* Corresponding author. cpark52{at}jh.edu
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Posted January 18, 2022.
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Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes
Chan-Su Park, Jian Guan, Peter Rhee, Federico Gonzalez, Laurent Coscoy, Ellen A. Robey, Nilabh Shastri, Scheherazade Sadegh-Nasseri
bioRxiv 2022.01.18.476719; doi: https://doi.org/10.1101/2022.01.18.476719
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Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes
Chan-Su Park, Jian Guan, Peter Rhee, Federico Gonzalez, Laurent Coscoy, Ellen A. Robey, Nilabh Shastri, Scheherazade Sadegh-Nasseri
bioRxiv 2022.01.18.476719; doi: https://doi.org/10.1101/2022.01.18.476719

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