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Caulobacter requires anionic sphingolipids and deactivation of fur to lose lipid A

View ORCID ProfileJustin J. Zik, Sung Hwan Yoon, Ziqiang Guan, Gabriele Stankeviciute Skidmore, Ridhi R. Gudoor, View ORCID ProfileKaren M. Davies, Adam M. Deutschbauer, View ORCID ProfileDavid R. Goodlett, View ORCID ProfileEric A. Klein, View ORCID ProfileKathleen R. Ryan
doi: https://doi.org/10.1101/2022.01.20.477143
Justin J. Zik
1Department of Plant & Microbial Biology, University of California, Berkeley, Berkeley, CA 94720 USA
12Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore
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Sung Hwan Yoon
2Department of Microbial Pathogenesis, University of Maryland School of Dentistry, Baltimore, MD 21201 USA
13National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892-0421 USA
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Ziqiang Guan
3Department of Biochemistry, Duke University Medical Center, Durham, NC 27710
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Gabriele Stankeviciute Skidmore
4Center for Computational and Integrative Biology, Rutgers University-Camden, Camden, NJ 08102 USA
11Rutgers Center for Lipid Research, Rutgers University, New Brunswick, NJ 08901 USA
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Ridhi R. Gudoor
5Molecular Biosciences and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA
6Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720 USA
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Karen M. Davies
5Molecular Biosciences and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA
6Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720 USA
14Diamond Light Source Ltd. Harwell Science & Innovation Campus, Didcot, Oxfordshire, OX11 0DE, UK
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Adam M. Deutschbauer
7Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA
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David R. Goodlett
2Department of Microbial Pathogenesis, University of Maryland School of Dentistry, Baltimore, MD 21201 USA
8Department of Biochemistry & Microbiology, University of Victoria, Victoria, BC V8W 2Y2 Canada
9University of Victoria-Genome BC Proteomics Centre, Victoria, BC V8Z 7X8 Canada
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Eric A. Klein
4Center for Computational and Integrative Biology, Rutgers University-Camden, Camden, NJ 08102 USA
10Biology Department, Rutgers University-Camden, Camden, NJ 08102 USA
11Rutgers Center for Lipid Research, Rutgers University, New Brunswick, NJ 08901 USA
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Kathleen R. Ryan
1Department of Plant & Microbial Biology, University of California, Berkeley, Berkeley, CA 94720 USA
7Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA
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  • For correspondence: krr@berkeley.edu
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Article Information

doi 
https://doi.org/10.1101/2022.01.20.477143
History 
  • January 21, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Justin J. Zik1,12,
  2. Sung Hwan Yoon2,13,
  3. Ziqiang Guan3,
  4. Gabriele Stankeviciute Skidmore4,11,
  5. Ridhi R. Gudoor5,6,
  6. Karen M. Davies5,6,14,
  7. Adam M. Deutschbauer7,
  8. David R. Goodlett2,8,9,
  9. Eric A. Klein4,10,11 and
  10. Kathleen R. Ryan1,7,*
  1. 1Department of Plant & Microbial Biology, University of California, Berkeley, Berkeley, CA 94720 USA
  2. 2Department of Microbial Pathogenesis, University of Maryland School of Dentistry, Baltimore, MD 21201 USA
  3. 3Department of Biochemistry, Duke University Medical Center, Durham, NC 27710
  4. 4Center for Computational and Integrative Biology, Rutgers University-Camden, Camden, NJ 08102 USA
  5. 5Molecular Biosciences and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA
  6. 6Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720 USA
  7. 7Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA
  8. 8Department of Biochemistry & Microbiology, University of Victoria, Victoria, BC V8W 2Y2 Canada
  9. 9University of Victoria-Genome BC Proteomics Centre, Victoria, BC V8Z 7X8 Canada
  10. 10Biology Department, Rutgers University-Camden, Camden, NJ 08102 USA
  11. 11Rutgers Center for Lipid Research, Rutgers University, New Brunswick, NJ 08901 USA
  12. 12Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore
  13. 13National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892-0421 USA
  14. 14Diamond Light Source Ltd. Harwell Science & Innovation Campus, Didcot, Oxfordshire, OX11 0DE, UK
  1. ↵*Correspondence: krr{at}berkeley.edu
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Caulobacter requires anionic sphingolipids and deactivation of fur to lose lipid A
Justin J. Zik, Sung Hwan Yoon, Ziqiang Guan, Gabriele Stankeviciute Skidmore, Ridhi R. Gudoor, Karen M. Davies, Adam M. Deutschbauer, David R. Goodlett, Eric A. Klein, Kathleen R. Ryan
bioRxiv 2022.01.20.477143; doi: https://doi.org/10.1101/2022.01.20.477143
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Caulobacter requires anionic sphingolipids and deactivation of fur to lose lipid A
Justin J. Zik, Sung Hwan Yoon, Ziqiang Guan, Gabriele Stankeviciute Skidmore, Ridhi R. Gudoor, Karen M. Davies, Adam M. Deutschbauer, David R. Goodlett, Eric A. Klein, Kathleen R. Ryan
bioRxiv 2022.01.20.477143; doi: https://doi.org/10.1101/2022.01.20.477143

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