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Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality
Sonia Sabate-Soler, Sarah Louise Nickels, Cláudia Saraiva, Emanuel Berger, Ugne Dubonyte, Kyriaki Barmpa, Yan Jun Lan, Tsukasa Kouno, Javier Jarazo, Graham Robertson, Jafar Sharif, Haruhiko Koseki, Christian Thome, Jay W. Shin, Sally A. Cowley, View ORCID ProfileJens C. Schwamborn
doi: https://doi.org/10.1101/2022.01.21.477192
Sonia Sabate-Soler
1Luxembourg Centre for Systems Biomedicine (LCSB), Developmental and Cellular Biology, University of Luxembourg, Belvaux, Luxembourg
Sarah Louise Nickels
1Luxembourg Centre for Systems Biomedicine (LCSB), Developmental and Cellular Biology, University of Luxembourg, Belvaux, Luxembourg
Cláudia Saraiva
1Luxembourg Centre for Systems Biomedicine (LCSB), Developmental and Cellular Biology, University of Luxembourg, Belvaux, Luxembourg
Emanuel Berger
1Luxembourg Centre for Systems Biomedicine (LCSB), Developmental and Cellular Biology, University of Luxembourg, Belvaux, Luxembourg
Ugne Dubonyte
1Luxembourg Centre for Systems Biomedicine (LCSB), Developmental and Cellular Biology, University of Luxembourg, Belvaux, Luxembourg
Kyriaki Barmpa
1Luxembourg Centre for Systems Biomedicine (LCSB), Developmental and Cellular Biology, University of Luxembourg, Belvaux, Luxembourg
Yan Jun Lan
3RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan
4ETH Zurich, Institute of Pharmaceutical Sciences, Zurich 8057 Switzerland
Tsukasa Kouno
3RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan
Javier Jarazo
1Luxembourg Centre for Systems Biomedicine (LCSB), Developmental and Cellular Biology, University of Luxembourg, Belvaux, Luxembourg
2OrganoTherapeutics SARL-S, Esch-sur-Alzette, Luxembourg
Graham Robertson
1Luxembourg Centre for Systems Biomedicine (LCSB), Developmental and Cellular Biology, University of Luxembourg, Belvaux, Luxembourg
Jafar Sharif
3RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan
Haruhiko Koseki
3RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan
Christian Thome
5Institute of Physiology and Pathophysiology, Heidelberg University, Heidelberg, Germany
Jay W. Shin
3RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan
Sally A. Cowley
6Oxford Parkinson’s Disease Centre, James Martin Stem Cell Facility, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
Jens C. Schwamborn
1Luxembourg Centre for Systems Biomedicine (LCSB), Developmental and Cellular Biology, University of Luxembourg, Belvaux, Luxembourg
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Posted January 22, 2022.
Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality
Sonia Sabate-Soler, Sarah Louise Nickels, Cláudia Saraiva, Emanuel Berger, Ugne Dubonyte, Kyriaki Barmpa, Yan Jun Lan, Tsukasa Kouno, Javier Jarazo, Graham Robertson, Jafar Sharif, Haruhiko Koseki, Christian Thome, Jay W. Shin, Sally A. Cowley, Jens C. Schwamborn
bioRxiv 2022.01.21.477192; doi: https://doi.org/10.1101/2022.01.21.477192
Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality
Sonia Sabate-Soler, Sarah Louise Nickels, Cláudia Saraiva, Emanuel Berger, Ugne Dubonyte, Kyriaki Barmpa, Yan Jun Lan, Tsukasa Kouno, Javier Jarazo, Graham Robertson, Jafar Sharif, Haruhiko Koseki, Christian Thome, Jay W. Shin, Sally A. Cowley, Jens C. Schwamborn
bioRxiv 2022.01.21.477192; doi: https://doi.org/10.1101/2022.01.21.477192
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