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The relaxin receptor RXFP1 signals through a mechanism of autoinhibition
Sarah C. Erlandson, Shaun Rawson, Kelly P. Brock, Xinyue Liu, Joao A. Paulo, Julian Mintseris, Steven P. Gygi, Debora S. Marks, View ORCID ProfileXiaojing Cong, View ORCID ProfileAndrew C. Kruse
doi: https://doi.org/10.1101/2022.01.22.477343
Sarah C. Erlandson
1Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
Shaun Rawson
1Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
Kelly P. Brock
2Department of Systems Biology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
Xinyue Liu
1Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
Joao A. Paulo
1Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
Julian Mintseris
1Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
Steven P. Gygi
1Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
Debora S. Marks
2Department of Systems Biology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
Xiaojing Cong
3Institut de Génomique Fonctionnelle, CNRS UMR5203-INSERM U1191-Université de Montpellier, 34090 Montpellier Cedex 5, France
Andrew C. Kruse
1Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
Posted January 23, 2022.
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition
Sarah C. Erlandson, Shaun Rawson, Kelly P. Brock, Xinyue Liu, Joao A. Paulo, Julian Mintseris, Steven P. Gygi, Debora S. Marks, Xiaojing Cong, Andrew C. Kruse
bioRxiv 2022.01.22.477343; doi: https://doi.org/10.1101/2022.01.22.477343
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition
Sarah C. Erlandson, Shaun Rawson, Kelly P. Brock, Xinyue Liu, Joao A. Paulo, Julian Mintseris, Steven P. Gygi, Debora S. Marks, Xiaojing Cong, Andrew C. Kruse
bioRxiv 2022.01.22.477343; doi: https://doi.org/10.1101/2022.01.22.477343
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