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Multiplexed strain phenotyping defines consequences of genetic diversity in Mycobacterium tuberculosis for infection and vaccination outcomes

View ORCID ProfileAllison F. Carey, Xin Wang, Nico Cicchetti, Caitlin N. Spaulding, Qingyun Liu, Forrest Hopkins, Jessica Brown, Jaimie Sixsmith, Thomas R. Ioerger, Sarah M. Fortune
doi: https://doi.org/10.1101/2022.01.23.477410
Allison F. Carey
1Department of Immunology & Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA
2Division of Microbiology & Immunology, Department of Pathology, University of Utah, Salt Lake City, UT
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  • ORCID record for Allison F. Carey
  • For correspondence: allison.carey@path.utah.edu sfortune@hsph.harvard.edu
Xin Wang
1Department of Immunology & Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA
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Nico Cicchetti
2Division of Microbiology & Immunology, Department of Pathology, University of Utah, Salt Lake City, UT
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Caitlin N. Spaulding
1Department of Immunology & Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA
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Qingyun Liu
1Department of Immunology & Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA
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Forrest Hopkins
1Department of Immunology & Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA
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Jessica Brown
1Department of Immunology & Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA
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Jaimie Sixsmith
1Department of Immunology & Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA
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Thomas R. Ioerger
3Department of Computer Science, Texas A&M University, College Station, TX
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Sarah M. Fortune
1Department of Immunology & Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA
4Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA
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  • For correspondence: allison.carey@path.utah.edu sfortune@hsph.harvard.edu
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Article Information

doi 
https://doi.org/10.1101/2022.01.23.477410
History 
  • January 24, 2022.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Allison F. Carey1,2,*,
  2. Xin Wang1,
  3. Nico Cicchetti2,
  4. Caitlin N. Spaulding1,
  5. Qingyun Liu1,
  6. Forrest Hopkins1,
  7. Jessica Brown1,
  8. Jaimie Sixsmith1,
  9. Thomas R. Ioerger3 and
  10. Sarah M. Fortune1,4,*
  1. 1Department of Immunology & Infectious Disease, Harvard T.H. Chan School of Public Health, Boston, MA
  2. 2Division of Microbiology & Immunology, Department of Pathology, University of Utah, Salt Lake City, UT
  3. 3Department of Computer Science, Texas A&M University, College Station, TX
  4. 4Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA
  1. ↵*Correspondence:
    Allison F. Carey (allison.carey{at}path.utah.edu) and Sarah M. Fortune (sfortune{at}hsph.harvard.edu)
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Posted January 24, 2022.
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Multiplexed strain phenotyping defines consequences of genetic diversity in Mycobacterium tuberculosis for infection and vaccination outcomes
Allison F. Carey, Xin Wang, Nico Cicchetti, Caitlin N. Spaulding, Qingyun Liu, Forrest Hopkins, Jessica Brown, Jaimie Sixsmith, Thomas R. Ioerger, Sarah M. Fortune
bioRxiv 2022.01.23.477410; doi: https://doi.org/10.1101/2022.01.23.477410
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Multiplexed strain phenotyping defines consequences of genetic diversity in Mycobacterium tuberculosis for infection and vaccination outcomes
Allison F. Carey, Xin Wang, Nico Cicchetti, Caitlin N. Spaulding, Qingyun Liu, Forrest Hopkins, Jessica Brown, Jaimie Sixsmith, Thomas R. Ioerger, Sarah M. Fortune
bioRxiv 2022.01.23.477410; doi: https://doi.org/10.1101/2022.01.23.477410

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