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Deconstructing replicative senescence heterogeneity of human mesenchymal stem cells at single cell resolution reveals therapeutically targetable senescent cell sub-populations
View ORCID ProfileAtefeh Taherian Fard, Hannah Leeson, Julio Aguado Perez, Giovanni Pietrogrande, Dominique Power, Cecilia Liliana Gomez Inclan, Huiwen Zheng, Christopher Nelson, Farhad Soheilmoghaddam, Nick Glass, Malindrie Dharmaratne, Ebony R. Watson, Jennifer Lu, Sally Martin, Hilda Pickett, Justin Cooper-White, Ernst Wolvetang, Jessica C. Mar
doi: https://doi.org/10.1101/2022.01.24.476823
Atefeh Taherian Fard
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
Hannah Leeson
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
Julio Aguado Perez
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
Giovanni Pietrogrande
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
Dominique Power
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
Cecilia Liliana Gomez Inclan
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
Huiwen Zheng
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
Christopher Nelson
2Children’s Medical Research Institute, Children’s Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia
Farhad Soheilmoghaddam
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
3School of Chemical Engineering, Faculty of Engineering, Architecture and Information Technology, The University of Queensland, Australia
Nick Glass
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
4PerkinElmer Pty Ltd, Glen Waverley VIC 3150, Australia
Malindrie Dharmaratne
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
Ebony R. Watson
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
Jennifer Lu
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
Sally Martin
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
Hilda Pickett
2Children’s Medical Research Institute, Children’s Medical Research Institute, University of Sydney, Westmead, New South Wales, Australia
Justin Cooper-White
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
3School of Chemical Engineering, Faculty of Engineering, Architecture and Information Technology, The University of Queensland, Australia
Ernst Wolvetang
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
Jessica C. Mar
1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Australia
Posted January 27, 2022.
Deconstructing replicative senescence heterogeneity of human mesenchymal stem cells at single cell resolution reveals therapeutically targetable senescent cell sub-populations
Atefeh Taherian Fard, Hannah Leeson, Julio Aguado Perez, Giovanni Pietrogrande, Dominique Power, Cecilia Liliana Gomez Inclan, Huiwen Zheng, Christopher Nelson, Farhad Soheilmoghaddam, Nick Glass, Malindrie Dharmaratne, Ebony R. Watson, Jennifer Lu, Sally Martin, Hilda Pickett, Justin Cooper-White, Ernst Wolvetang, Jessica C. Mar
bioRxiv 2022.01.24.476823; doi: https://doi.org/10.1101/2022.01.24.476823
Deconstructing replicative senescence heterogeneity of human mesenchymal stem cells at single cell resolution reveals therapeutically targetable senescent cell sub-populations
Atefeh Taherian Fard, Hannah Leeson, Julio Aguado Perez, Giovanni Pietrogrande, Dominique Power, Cecilia Liliana Gomez Inclan, Huiwen Zheng, Christopher Nelson, Farhad Soheilmoghaddam, Nick Glass, Malindrie Dharmaratne, Ebony R. Watson, Jennifer Lu, Sally Martin, Hilda Pickett, Justin Cooper-White, Ernst Wolvetang, Jessica C. Mar
bioRxiv 2022.01.24.476823; doi: https://doi.org/10.1101/2022.01.24.476823
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