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Human NLRP1 is activated by ZAKɑ-driven ribotoxic stress response
Kim S. Robinson, Gee Ann Toh, Pritisha Rozario, Shima Bayat, Zijin Sun, Stefan Bauernfried, Rhea Nadkarni, Cassandra R. Harapas, Chrissie K. Lim, Werncui Chu, Kiat Yi Tan, Carine Bonnard, Radoslaw Sobota, John E. Connolly, Seth L. Masters, Kaiwen W. Chen, Lena Ho, Veit Hornung, Franklin L. Zhong
doi: https://doi.org/10.1101/2022.01.24.477516
Kim S. Robinson
1Skin Research Institute of Singapore (SRIS), #17-01 Clinical Sciences Building, 11 Mandalay Road, 308232, Singapore
Gee Ann Toh
2Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, 308232, Singapore
Pritisha Rozario
2Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, 308232, Singapore
Shima Bayat
2Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, 308232, Singapore
Zijin Sun
2Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, 308232, Singapore
Stefan Bauernfried
6Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany
7Max-Planck Institute of Biochemistry, Martinsried, Germany
Rhea Nadkarni
3Cardiovascular Metabolic Disorders Program, Duke-NUS Medical School, 8 College Road, 169857, Singapore
Cassandra R. Harapas
4Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia
Chrissie K. Lim
8Institute of Molecular and Cell Biology, A*STAR, Singapore
Werncui Chu
3Cardiovascular Metabolic Disorders Program, Duke-NUS Medical School, 8 College Road, 169857, Singapore
Kiat Yi Tan
9Immunology Translational Research Programme and Department of Microbiology & Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Carine Bonnard
Radoslaw Sobota
8Institute of Molecular and Cell Biology, A*STAR, Singapore
John E. Connolly
9Immunology Translational Research Programme and Department of Microbiology & Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Seth L. Masters
4Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Australia
5Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia
Kaiwen W. Chen
9Immunology Translational Research Programme and Department of Microbiology & Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Lena Ho
3Cardiovascular Metabolic Disorders Program, Duke-NUS Medical School, 8 College Road, 169857, Singapore
8Institute of Molecular and Cell Biology, A*STAR, Singapore
Veit Hornung
6Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany
7Max-Planck Institute of Biochemistry, Martinsried, Germany
Franklin L. Zhong
1Skin Research Institute of Singapore (SRIS), #17-01 Clinical Sciences Building, 11 Mandalay Road, 308232, Singapore
2Lee Kong Chian School of Medicine, Nanyang Technological University, 11 Mandalay Road, 308232, Singapore
Article usage
Posted January 25, 2022.
Human NLRP1 is activated by ZAKɑ-driven ribotoxic stress response
Kim S. Robinson, Gee Ann Toh, Pritisha Rozario, Shima Bayat, Zijin Sun, Stefan Bauernfried, Rhea Nadkarni, Cassandra R. Harapas, Chrissie K. Lim, Werncui Chu, Kiat Yi Tan, Carine Bonnard, Radoslaw Sobota, John E. Connolly, Seth L. Masters, Kaiwen W. Chen, Lena Ho, Veit Hornung, Franklin L. Zhong
bioRxiv 2022.01.24.477516; doi: https://doi.org/10.1101/2022.01.24.477516
Human NLRP1 is activated by ZAKɑ-driven ribotoxic stress response
Kim S. Robinson, Gee Ann Toh, Pritisha Rozario, Shima Bayat, Zijin Sun, Stefan Bauernfried, Rhea Nadkarni, Cassandra R. Harapas, Chrissie K. Lim, Werncui Chu, Kiat Yi Tan, Carine Bonnard, Radoslaw Sobota, John E. Connolly, Seth L. Masters, Kaiwen W. Chen, Lena Ho, Veit Hornung, Franklin L. Zhong
bioRxiv 2022.01.24.477516; doi: https://doi.org/10.1101/2022.01.24.477516
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