A quantitative model for the dynamics of target recognition and off-target rejection by the CRISPR-Cas Cascade complex

Marius Rutkauskas; Inga Songailiene; Patrick Irmisch; Felix E. Kemmerich; Tomas Sinkunas; Virginijus Siksnys; Ralf Seidel

doi:10.1101/2022.01.26.477710

New Results

A quantitative model for the dynamics of target recognition and off-target rejection by the CRISPR-Cas Cascade complex

Marius Rutkauskas, Inga Songailiene, Patrick Irmisch, Felix E. Kemmerich, Tomas Sinkunas, Virginijus Siksnys, Ralf Seidel

doi: https://doi.org/10.1101/2022.01.26.477710

Marius Rutkauskas

1Peter Debye Institute for Soft Matter Physics, Universität Leipzig, 04103 Leipzig, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Inga Songailiene

2Institute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekis ave. 7, Vilnius 10257, Lithuania

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Patrick Irmisch

1Peter Debye Institute for Soft Matter Physics, Universität Leipzig, 04103 Leipzig, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Felix E. Kemmerich

1Peter Debye Institute for Soft Matter Physics, Universität Leipzig, 04103 Leipzig, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Tomas Sinkunas

2Institute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekis ave. 7, Vilnius 10257, Lithuania

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Virginijus Siksnys

2Institute of Biotechnology, Life Sciences Center, Vilnius University, Saulėtekis ave. 7, Vilnius 10257, Lithuania

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ralf Seidel

1Peter Debye Institute for Soft Matter Physics, Universität Leipzig, 04103 Leipzig, Germany

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: ralf.seidel@physik.uni-leipzig.de

Abstract
Full Text
Info/History
Metrics
Preview PDF

Article usage

Article usage: January 2022 to June 2022

	Abstract	Full	Pdf
Jan 2022	700	3	105
Feb 2022	191	67	65
Mar 2022	87	16	29
Apr 2022	44	6	12
May 2022	27	1	15
Jun 2022	32	4	9

View the discussion thread.

PreviousNext

Posted January 26, 2022.

Download PDF

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following A quantitative model for the dynamics of target recognition and off-target rejection by the CRISPR-Cas Cascade complex

Message Subject (Your Name) has forwarded a page to you from bioRxiv

Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

A quantitative model for the dynamics of target recognition and off-target rejection by the CRISPR-Cas Cascade complex

Marius Rutkauskas, Inga Songailiene, Patrick Irmisch, Felix E. Kemmerich, Tomas Sinkunas, Virginijus Siksnys, Ralf Seidel

bioRxiv 2022.01.26.477710; doi: https://doi.org/10.1101/2022.01.26.477710

Share This Article:

Citation Tools

A quantitative model for the dynamics of target recognition and off-target rejection by the CRISPR-Cas Cascade complex

Marius Rutkauskas, Inga Songailiene, Patrick Irmisch, Felix E. Kemmerich, Tomas Sinkunas, Virginijus Siksnys, Ralf Seidel

bioRxiv 2022.01.26.477710; doi: https://doi.org/10.1101/2022.01.26.477710

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Tweet Widget
Facebook Like
Google Plus One

Subject Area

Biophysics

Subject Areas

All Articles

Animal Behavior and Cognition (3585)
Biochemistry (7539)
Bioengineering (5494)
Bioinformatics (20724)
Biophysics (10292)
Cancer Biology (7946)
Cell Biology (11609)
Clinical Trials (138)
Developmental Biology (6584)
Ecology (10161)
Epidemiology (2065)
Evolutionary Biology (13573)
Genetics (9511)
Genomics (12811)
Immunology (7900)
Microbiology (19490)
Molecular Biology (7632)
Neuroscience (41969)
Paleontology (307)
Pathology (1254)
Pharmacology and Toxicology (2189)
Physiology (3258)
Plant Biology (7017)
Scientific Communication and Education (1293)
Synthetic Biology (1946)
Systems Biology (5417)
Zoology (1112)