New Results
Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh Syndrome
View ORCID ProfileAlessandro Bitto, View ORCID ProfileAnthony S. Grillo, View ORCID ProfileIan B. Stanaway, Bao M. G. Nguyen, View ORCID ProfileKejun Ying, View ORCID ProfileHerman Tung, Kaleb Smith, Ngoc Tran, Gunnar Velikanje, View ORCID ProfileSilvan R. Urfer, Jessica M. Snyder, View ORCID ProfileErnst-Bernhard Kayser, Lu Wang, Daniel L. Smith Jr., View ORCID ProfileJ. Will Thompson, Laura DuBois, View ORCID ProfileWilliam DePaolo, View ORCID ProfileMatt Kaeberlein
doi: https://doi.org/10.1101/2022.01.31.478591
Alessandro Bitto
1Department of Laboratory Medicine and Pathology, University of Washington, Seattle WA
Anthony S. Grillo
1Department of Laboratory Medicine and Pathology, University of Washington, Seattle WA
Ian B. Stanaway
2Department of Microbiology, University of Washington, Seattle WA
Bao M. G. Nguyen
1Department of Laboratory Medicine and Pathology, University of Washington, Seattle WA
Kejun Ying
3T.H. Chan School of Public Health, Harvard University, Boston MA
Herman Tung
4Shape Therapeutics, Seattle WA
Kaleb Smith
5Seattle Genetics, Seattle WA
Ngoc Tran
1Department of Laboratory Medicine and Pathology, University of Washington, Seattle WA
Gunnar Velikanje
1Department of Laboratory Medicine and Pathology, University of Washington, Seattle WA
Silvan R. Urfer
1Department of Laboratory Medicine and Pathology, University of Washington, Seattle WA
Jessica M. Snyder
6Department of Comparative Medicine, University of Washington, Seattle WA
Ernst-Bernhard Kayser
7Seattle Children’s Research Institute, Seattle WA
Lu Wang
8Department of Environmental and Occupational Health Sciences, University of Washington, Seattle WA
Daniel L. Smith Jr.
9Department of Nutrition Sciences University of Alabama at Birmingham, Birmingham AL
J. Will Thompson
10Department of Pharmacology and Cancer Biology, Duke University, Durham NC
Laura DuBois
11Department of Biostatistics and Bioinformatics, Duke University, Durham NC
William DePaolo
12Department of Microbiology, University of Washington, Seattle WA
Matt Kaeberlein
1Department of Laboratory Medicine and Pathology, University of Washington, Seattle WA
Article usage
Posted February 01, 2022.
Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh Syndrome
Alessandro Bitto, Anthony S. Grillo, Ian B. Stanaway, Bao M. G. Nguyen, Kejun Ying, Herman Tung, Kaleb Smith, Ngoc Tran, Gunnar Velikanje, Silvan R. Urfer, Jessica M. Snyder, Ernst-Bernhard Kayser, Lu Wang, Daniel L. Smith Jr., J. Will Thompson, Laura DuBois, William DePaolo, Matt Kaeberlein
bioRxiv 2022.01.31.478591; doi: https://doi.org/10.1101/2022.01.31.478591
Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh Syndrome
Alessandro Bitto, Anthony S. Grillo, Ian B. Stanaway, Bao M. G. Nguyen, Kejun Ying, Herman Tung, Kaleb Smith, Ngoc Tran, Gunnar Velikanje, Silvan R. Urfer, Jessica M. Snyder, Ernst-Bernhard Kayser, Lu Wang, Daniel L. Smith Jr., J. Will Thompson, Laura DuBois, William DePaolo, Matt Kaeberlein
bioRxiv 2022.01.31.478591; doi: https://doi.org/10.1101/2022.01.31.478591
Subject Area
Subject Areas
- Biochemistry (11753)
- Bioengineering (8752)
- Bioinformatics (29201)
- Biophysics (14974)
- Cancer Biology (12100)
- Cell Biology (17413)
- Clinical Trials (138)
- Developmental Biology (9422)
- Ecology (14182)
- Epidemiology (2067)
- Evolutionary Biology (18309)
- Genetics (12245)
- Genomics (16804)
- Immunology (11869)
- Microbiology (28098)
- Molecular Biology (11596)
- Neuroscience (60975)
- Paleontology (451)
- Pathology (1871)
- Pharmacology and Toxicology (3238)
- Physiology (4959)
- Plant Biology (10427)
- Synthetic Biology (2886)
- Systems Biology (7340)
- Zoology (1651)