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Coupling comprehensive pesticide-wide association study to iPSC dopaminergic screening identifies and classifies Parkinson-relevant pesticides
View ORCID ProfileKimberly C Paul, View ORCID ProfileRichard C Krolewski, View ORCID ProfileEdinson Lucumi Moreno, Jack Blank, Kris Holton, Tim Ahfeldt, Melissa Furlong, Yu Yu, Myles Cockburn, Laura K Thompson, Jeff Bronstein, View ORCID ProfileLee L. Rubin, View ORCID ProfileVikram Khurana, View ORCID ProfileBeate Ritz
doi: https://doi.org/10.1101/2022.02.06.479305
Kimberly C Paul
1Department of Neurology, UCLA David Geffen School of Medicine, Los Angeles, California, USA
Richard C Krolewski
2Department of Neurology, Brigham and Women’s Hospital, Boston, MA, USA
3Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA
Edinson Lucumi Moreno
2Department of Neurology, Brigham and Women’s Hospital, Boston, MA, USA
Jack Blank
4Prime Medicine, Inc. Cambridge, MA, USA
Kris Holton
3Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA
Tim Ahfeldt
5Recursion Pharmaceuticals, Salt Lake City, UT, USA
6Nash Family Department of Neuroscience at Mount Sinai, New York, NY, USA
Melissa Furlong
7University of Arizona, Mel and Enid Zuckerman College of Public Health, Tucson, Arizona, USA
Yu Yu
8Center for Health Policy Research, UCLA Fielding School of Public Health, Los Angeles, California, USA
Myles Cockburn
9Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, CA, USA
Laura K Thompson
9Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, CA, USA
Jeff Bronstein
1Department of Neurology, UCLA David Geffen School of Medicine, Los Angeles, California, USA
Lee L. Rubin
3Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA
11Harvard Stem Cell Institute, Cambridge, MA, USA
Vikram Khurana
2Department of Neurology, Brigham and Women’s Hospital, Boston, MA, USA
Beate Ritz
1Department of Neurology, UCLA David Geffen School of Medicine, Los Angeles, California, USA
10Department of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, California, USA
Posted February 09, 2022.
Coupling comprehensive pesticide-wide association study to iPSC dopaminergic screening identifies and classifies Parkinson-relevant pesticides
Kimberly C Paul, Richard C Krolewski, Edinson Lucumi Moreno, Jack Blank, Kris Holton, Tim Ahfeldt, Melissa Furlong, Yu Yu, Myles Cockburn, Laura K Thompson, Jeff Bronstein, Lee L. Rubin, Vikram Khurana, Beate Ritz
bioRxiv 2022.02.06.479305; doi: https://doi.org/10.1101/2022.02.06.479305
Coupling comprehensive pesticide-wide association study to iPSC dopaminergic screening identifies and classifies Parkinson-relevant pesticides
Kimberly C Paul, Richard C Krolewski, Edinson Lucumi Moreno, Jack Blank, Kris Holton, Tim Ahfeldt, Melissa Furlong, Yu Yu, Myles Cockburn, Laura K Thompson, Jeff Bronstein, Lee L. Rubin, Vikram Khurana, Beate Ritz
bioRxiv 2022.02.06.479305; doi: https://doi.org/10.1101/2022.02.06.479305
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