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Boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibody responses and protection against B.1.1.529 infection in mice
Baoling Ying, Suzanne M. Scheaffer, Bradley Whitener, Chieh-Yu Liang, Oleksandr Dmytrenko, Samantha Mackin, Kai Wu, Diana Lee, Laura E. Avena, Zhenlu Chong, James Brett Case, LingZhi Ma, Thu Kim, Caralyn Sein, Angela Woods, Daniela Montes Berrueta, Andrea Carfi, Sayda M. Elbashir, Darin K. Edwards, Larissa B. Thackray, View ORCID ProfileMichael S. Diamond
doi: https://doi.org/10.1101/2022.02.07.479419
Baoling Ying
1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
Suzanne M. Scheaffer
1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
Bradley Whitener
1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
Chieh-Yu Liang
1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
2Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA
Oleksandr Dmytrenko
1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
Samantha Mackin
1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
2Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA
Kai Wu
3Moderna, Inc., Cambridge MA, USA
Diana Lee
3Moderna, Inc., Cambridge MA, USA
Laura E. Avena
3Moderna, Inc., Cambridge MA, USA
Zhenlu Chong
1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
James Brett Case
1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
LingZhi Ma
3Moderna, Inc., Cambridge MA, USA
Thu Kim
3Moderna, Inc., Cambridge MA, USA
Caralyn Sein
3Moderna, Inc., Cambridge MA, USA
Angela Woods
3Moderna, Inc., Cambridge MA, USA
Daniela Montes Berrueta
3Moderna, Inc., Cambridge MA, USA
Andrea Carfi
3Moderna, Inc., Cambridge MA, USA
Sayda M. Elbashir
3Moderna, Inc., Cambridge MA, USA
Darin K. Edwards
3Moderna, Inc., Cambridge MA, USA
Larissa B. Thackray
1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
Michael S. Diamond
1Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
2Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA
4Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA
5The Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine. St. Louis, MO, USA
6Center for Vaccines and Immunity to Microbial Pathogens, Washington University School of Medicine, Saint Louis, MO, USA
Posted February 09, 2022.
Boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibody responses and protection against B.1.1.529 infection in mice
Baoling Ying, Suzanne M. Scheaffer, Bradley Whitener, Chieh-Yu Liang, Oleksandr Dmytrenko, Samantha Mackin, Kai Wu, Diana Lee, Laura E. Avena, Zhenlu Chong, James Brett Case, LingZhi Ma, Thu Kim, Caralyn Sein, Angela Woods, Daniela Montes Berrueta, Andrea Carfi, Sayda M. Elbashir, Darin K. Edwards, Larissa B. Thackray, Michael S. Diamond
bioRxiv 2022.02.07.479419; doi: https://doi.org/10.1101/2022.02.07.479419
Boosting with Omicron-matched or historical mRNA vaccines increases neutralizing antibody responses and protection against B.1.1.529 infection in mice
Baoling Ying, Suzanne M. Scheaffer, Bradley Whitener, Chieh-Yu Liang, Oleksandr Dmytrenko, Samantha Mackin, Kai Wu, Diana Lee, Laura E. Avena, Zhenlu Chong, James Brett Case, LingZhi Ma, Thu Kim, Caralyn Sein, Angela Woods, Daniela Montes Berrueta, Andrea Carfi, Sayda M. Elbashir, Darin K. Edwards, Larissa B. Thackray, Michael S. Diamond
bioRxiv 2022.02.07.479419; doi: https://doi.org/10.1101/2022.02.07.479419
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