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Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein (IL-18BP) in inflammation and tumor immunity
View ORCID ProfileSammy Detry, View ORCID ProfileJulie Andries, View ORCID ProfileYehudi Bloch, View ORCID ProfileCem Gabay, View ORCID ProfileDanielle Clancy, View ORCID ProfileSavvas N. Savvides
doi: https://doi.org/10.1101/2022.02.10.479912
Sammy Detry
1Unit for Structural Biology, Department of Biochemistry and Microbiology, Ghent University, Technologiepark 71, 9052 Ghent, Belgium
2Unit for Structural Biology, VIB Center for Inflammation Research, Technologiepark 71, 9052 Ghent, Belgium
Julie Andries
1Unit for Structural Biology, Department of Biochemistry and Microbiology, Ghent University, Technologiepark 71, 9052 Ghent, Belgium
2Unit for Structural Biology, VIB Center for Inflammation Research, Technologiepark 71, 9052 Ghent, Belgium
Yehudi Bloch
1Unit for Structural Biology, Department of Biochemistry and Microbiology, Ghent University, Technologiepark 71, 9052 Ghent, Belgium
2Unit for Structural Biology, VIB Center for Inflammation Research, Technologiepark 71, 9052 Ghent, Belgium
Cem Gabay
3Division of Rheumatology, Department of Medicine, Geneva University Hospitals & Faculty of Medicine University of Geneva, CH-1211 Geneva 14, Switzerland
Danielle Clancy
1Unit for Structural Biology, Department of Biochemistry and Microbiology, Ghent University, Technologiepark 71, 9052 Ghent, Belgium
2Unit for Structural Biology, VIB Center for Inflammation Research, Technologiepark 71, 9052 Ghent, Belgium
Savvas N. Savvides
1Unit for Structural Biology, Department of Biochemistry and Microbiology, Ghent University, Technologiepark 71, 9052 Ghent, Belgium
2Unit for Structural Biology, VIB Center for Inflammation Research, Technologiepark 71, 9052 Ghent, Belgium
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Posted February 10, 2022.
Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein (IL-18BP) in inflammation and tumor immunity
Sammy Detry, Julie Andries, Yehudi Bloch, Cem Gabay, Danielle Clancy, Savvas N. Savvides
bioRxiv 2022.02.10.479912; doi: https://doi.org/10.1101/2022.02.10.479912
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