Sequence- and chemical specificity define the functional landscape of intrinsically disordered regions

Iris Langstein-Skora; Andrea Schmid; Ryan J. Emenecker; Mary O.G. Richardson; Maximilian J. Götz; Sarah K. Payer; Philipp Korber; Alex S. Holehouse

doi:10.1101/2022.02.10.480018

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Sequence- and chemical specificity define the functional landscape of intrinsically disordered regions

Iris Langstein-Skora, Andrea Schmid, View ORCID ProfileRyan J. Emenecker, View ORCID ProfileMary O.G. Richardson, Maximilian J. Götz, Sarah K. Payer, View ORCID ProfilePhilipp Korber, View ORCID ProfileAlex S. Holehouse

doi: https://doi.org/10.1101/2022.02.10.480018

Iris Langstein-Skora

1Biomedical Center (BMC), Division of Molecular Biology, Faculty of Medicine, LMU Munich, Martinsried, Germany

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Andrea Schmid

1Biomedical Center (BMC), Division of Molecular Biology, Faculty of Medicine, LMU Munich, Martinsried, Germany

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Ryan J. Emenecker

2Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA

3Center for Science and Engineering Living Systems, Washington University, St. Louis, MO, USA

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ORCID record for Ryan J. Emenecker

Mary O.G. Richardson

3Center for Science and Engineering Living Systems, Washington University, St. Louis, MO, USA

4Department of Molecular & Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America

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Maximilian J. Götz

1Biomedical Center (BMC), Division of Molecular Biology, Faculty of Medicine, LMU Munich, Martinsried, Germany

5Gene Center and Department of Biochemistry, LMU Munich, Munich, Germany

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Sarah K. Payer

1Biomedical Center (BMC), Division of Molecular Biology, Faculty of Medicine, LMU Munich, Martinsried, Germany

6Proteros Biostructures GmbH, Martinsried, Germany

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Philipp Korber

1Biomedical Center (BMC), Division of Molecular Biology, Faculty of Medicine, LMU Munich, Martinsried, Germany

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For correspondence: [email protected] [email protected]

Alex S. Holehouse

2Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA

3Center for Science and Engineering Living Systems, Washington University, St. Louis, MO, USA

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For correspondence: [email protected] [email protected]

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Posted February 11, 2022.

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Sequence- and chemical specificity define the functional landscape of intrinsically disordered regions

Iris Langstein-Skora, Andrea Schmid, Ryan J. Emenecker, Mary O.G. Richardson, Maximilian J. Götz, Sarah K. Payer, Philipp Korber, Alex S. Holehouse

bioRxiv 2022.02.10.480018; doi: https://doi.org/10.1101/2022.02.10.480018

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Sequence- and chemical specificity define the functional landscape of intrinsically disordered regions

Iris Langstein-Skora, Andrea Schmid, Ryan J. Emenecker, Mary O.G. Richardson, Maximilian J. Götz, Sarah K. Payer, Philipp Korber, Alex S. Holehouse

bioRxiv 2022.02.10.480018; doi: https://doi.org/10.1101/2022.02.10.480018

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